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Neurotoxicity Syndromes
Known as:
Neurotoxin Disease
, NEUROTIC TOXICITY
, Neurotoxic Disorder
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A group of neurologic disorders caused by damage to the nervous system following exposure to pharmacologic, biologic, and chemical agents. Examples…
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National Institutes of Health
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Related topics
Related topics
14 relations
Narrower (2)
Encephalopathy, Toxic
Toxic Encephalitis
In Blood
Microbiological
Nerve Tissue
Nervous system structure
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Broader (1)
nervous system disorder
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Neurotoxic reactive astrocytes are induced by activated microglia
S. Liddelow
,
Kevin A. Guttenplan
,
+18 authors
B. Barres
Nature
2017
Corpus ID: 4392944
Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood…
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Highly Cited
2009
Highly Cited
2009
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.
T. Mok
,
Yi-long Wu
,
+16 authors
M. Fukuoka
New England Journal of Medicine
2009
Corpus ID: 3170875
BACKGROUND Previous, uncontrolled studies have suggested that first-line treatment with gefitinib would be efficacious in…
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Review
2007
Review
2007
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
M. Block
,
L. Zecca
,
Jau-Shyong Hong
Nature Reviews Neuroscience
2007
Corpus ID: 1310155
Mounting evidence indicates that microglial activation contributes to neuronal damage in neurodegenerative diseases. Recent…
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Review
2007
Review
2007
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
U. Hanisch
,
H. Kettenmann
Nature Neuroscience
2007
Corpus ID: 28301217
Microglial cells constitute the resident macrophage population of the CNS. Recent in vivo studies have shown that microglia carry…
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Highly Cited
2002
Highly Cited
2002
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
D. Walsh
,
I. Klyubin
,
+5 authors
D. Selkoe
Nature
2002
Corpus ID: 4423021
Although extensive data support a central pathogenic role for amyloid β protein (Aβ) in Alzheimer's disease, the amyloid…
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Highly Cited
2000
Highly Cited
2000
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
T. Nakagawa
,
Hong Zhu
,
+4 authors
Junying Yuan
Nature
2000
Corpus ID: 205065930
Apoptosis, or cellular suicide, is important for normal development and tissue homeostasis, but too much or too little apoptosis…
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Highly Cited
1998
Highly Cited
1998
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.
M. Lambert
,
A. Barlow
,
+12 authors
W. Klein
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 28329526
Abeta1-42 is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer's pathogenesis…
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Highly Cited
1997
Highly Cited
1997
Agency for Toxic Substances and Disease Registry.
Foreword
Asian American and Pacific Islander journal of…
1997
Corpus ID: 32846149
The mission of the Agency for Toxic Substances and Disease Registry (ATSDR) is to prevent or mitigate the adverse human health…
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Review
1992
Review
1992
Reactive Oxygen Species and the Central Nervous System
B. Halliwell
Journal of Neurochemistry
1992
Corpus ID: 77937
Abstract: Radicals are species containing one or more unpaired electrons, such as nitric oxide (NO•−). The oxygen radical…
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Review
1988
Review
1988
Glutamate neurotoxicity and diseases of the nervous system
D. Choi
Neuron
1988
Corpus ID: 2435160
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