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Neurotoxicity Syndromes

Known as: Neurotoxin Disease, NEUROTIC TOXICITY, Neurotoxic Disorder 
A group of neurologic disorders caused by damage to the nervous system following exposure to pharmacologic, biologic, and chemical agents. Examples… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (2)

Encephalopathy, ToxicToxic Encephalitis
In BloodMicrobiologicalNerve TissueNervous system structure

Broader (1)

nervous system disorder

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Neurotoxic reactive astrocytes are induced by activated microglia
Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood… 
Highly Cited
2009
Highly Cited
2009
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.
BACKGROUND Previous, uncontrolled studies have suggested that first-line treatment with gefitinib would be efficacious in… 
Review
2007
Review
2007
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Mounting evidence indicates that microglial activation contributes to neuronal damage in neurodegenerative diseases. Recent… 
Review
2007
Review
2007
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Microglial cells constitute the resident macrophage population of the CNS. Recent in vivo studies have shown that microglia carry… 
Highly Cited
2002
Highly Cited
2002
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
Although extensive data support a central pathogenic role for amyloid β protein (Aβ) in Alzheimer's disease, the amyloid… 
Highly Cited
2000
Highly Cited
2000
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
Apoptosis, or cellular suicide, is important for normal development and tissue homeostasis, but too much or too little apoptosis… 
Highly Cited
1998
Highly Cited
1998
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.
Abeta1-42 is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer's pathogenesis… 
Highly Cited
1997
Highly Cited
1997
Agency for Toxic Substances and Disease Registry.
  • Foreword
  • Asian American and Pacific Islander journal of…
  • 1997
  • Corpus ID: 32846149
The mission of the Agency for Toxic Substances and Disease Registry (ATSDR) is to prevent or mitigate the adverse human health… 
Review
1992
Review
1992
Reactive Oxygen Species and the Central Nervous System
Abstract: Radicals are species containing one or more unpaired electrons, such as nitric oxide (NO•−). The oxygen radical… 
Review
1988
Review
1988
Glutamate neurotoxicity and diseases of the nervous system
  • D. Choi
  • Neuron
  • 1988
  • Corpus ID: 2435160
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