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&NA; Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and synaptic efficacy of neurons in… Expand UNLABELLED
Central sensitization represents an enhancement in the function of neurons and circuits in nociceptive pathways caused… Expand Pain usually results from activation of nociceptive afferents by actually or potentially tissue-damaging stimuli. Pain may also… Expand Abstract Patients with neuropathic pain (NP) are challenging to manage and evidence‐based clinical recommendations for… Expand Acute postoperative pain is followed by persistent pain in 10-50% of individuals after common operations, such as groin hernia… Expand We describe those sensations that are unpleasant, intense, or distressing as painful. Pain is not homogeneous, however, and… Expand We highlight current theories about peripheral neuropathic pain and show that progress in management is contingent on targeting… Expand We applied and validated a quantitative allodynia assessment technique, using a recently developed rat surgical neuropathy model… Expand We attempted to develop an experimental animal model for peripheral neuropathic pain. Under sodium pentobarbital anesthesia, both… Expand &NA; A peripheral mononeuropathy was produced in adult rats by placing loosely constrictive ligatures around the common sciatic… Expand