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Neopterin

Known as: 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone, 4(1H)-Pteridinone, 2-Amino-6-(1,2,3-Trihydroxypropyl)-, Neopterin [Chemical/Ingredient] 
A pteridine that is a metabolite of guanine triphosphate (GTP) and a precursor for biopterin. Neopterin is released from interferon-gamma (IFNg… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (4)

7,8-dihydroneopterinNeopterin, (erythro-D)-Isomerdihydroneopterin triphosphatesolfapterin

Broader (1)

Biopterin
In BloodNeopterin [Mass or Molecules/volume] in Serum or PlasmaNeopterin/Creatinine:MRto:Pt:Urine:QnNeopterin:Mass:Pt:Dose:Qn

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Diagnosis, classification, and genetics of phenylketonuria and tetrahydrobiopterin (BH4) deficiencies.
Highly Cited
2002
Highly Cited
2002
A randomized, double-blind, dose-comparison study of weekly interferon β-1a in relapsing MS
Background: Interferon β-1a (IFNβ-1a; Avonex) is effective for the treatment of relapsing MS; however, the optimal dose of IFN… 
Highly Cited
2000
Highly Cited
2000
Pegylated interferon‐α2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data
The objectives of this study were to assess the safety, pharmacokinetic and pharmacodynamic profiles, and antiviral efficacy of… 
Review
1999
Review
1999
Neopterin: a review
Abstract: Neopterin was discovered in bee larvae, in worker bees and in royal jelly. The compound was termed “neopterin” to… 
Highly Cited
1997
Highly Cited
1997
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies.
A Phase I dose escalation trial of i.v. administered recombinant human interleukin 12 (rhIL-12) was performed to determine its… 
Review
1995
Review
1995
Quantitation of HIV-1 RNA in Plasma Predicts Outcome after Seroconversion
The course of infection with human immunodeficiency virus type 1 (HIV-1) varies considerably. Although the median interval… 
Highly Cited
1994
Highly Cited
1994
Hypozincemia in depression.
Highly Cited
1990
Highly Cited
1990
Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase…
Review
1988
Review
1988
Neopterin as a marker for activated cell-mediated immunity: application in HIV infection.
Highly Cited
1987
Highly Cited
1987
Human macrophages degrade tryptophan upon induction by interferon-gamma.
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