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7,8-dihydroneopterin
Known as:
2-amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone
, 7,8-dihydro-neopterin
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Neopterin
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Dissociation of neopterin and 7,8-dihydroneopterin from plasma components before HPLC analysis.
E. Flavall
,
E. Crone
,
G. Moore
,
S. Gieseg
Journal of chromatography. B, Analytical…
2008
Corpus ID: 22079725
Measurement of plasma neopterin by HPLC with fluorescence detection is used clinically as a marker of immune cell activation in…
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2001
2001
Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin
S. Gieseg
,
J. Whybrow
,
Dylan M Glubb
,
C. Rait
Free radical research
2001
Corpus ID: 39095399
Interferon-γ stimulation of human macrophages causes the synthesis and release of neopterin and its reduced form 7,8…
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2001
2001
Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin
S. Gieseg
,
G. Maghzal
,
Dylan M Glubb
Free radical research
2001
Corpus ID: 34929458
Neopterin and the reduced form, 7,8-dihydroneopterin (78NP), are pteridines released from macrophages when stimulated with…
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2000
2000
Oxidation of 7,8-dihydroneopterin by hypochlorous acid yields neopterin.
B. Widner
,
C. Mayr
,
B. Wirleitner
,
D. Fuchs
Biochemical and biophysical research…
2000
Corpus ID: 22268291
In vitro, interferon-gamma stimulates primate monocytes/macrophages to produce the pteridines neopterin and 7,8-dihydroneopterin…
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1999
1999
Formation of oxygen radicals in solutions of 7,8-dihydroneopterin.
K. Oettl
,
B. Wirleitner
,
G. Baier-Bitterlich
,
T. Grammer
,
D. Fuchs
,
G. Reibnegger
Biochemical and biophysical research…
1999
Corpus ID: 26287003
Neopterin and 7,8-dihydroneopterin, two compounds which are secreted by activated macrophages, have been shown to interfere with…
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Highly Cited
1998
Highly Cited
1998
Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from staphylococcus aureus
Michael Hennig
,
A. D'arcy
,
I. C. Hampele
,
M. Page
,
C. Oefner
,
G. Dale
Nature Structural Biology
1998
Corpus ID: 24947798
Dihydroneopterin aldolase catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin during the de…
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1997
1997
Spin trapping study of antioxidant properties of neopterin and 7,8-dihydroneopterin.
K. Oettl
,
S. Dikalov
,
H. Freisleben
,
W. Mlekusch
,
G. Reibnegger
Biochemical and biophysical research…
1997
Corpus ID: 34768011
Previously, it has been shown that pteridine derivatives are capable of modulating the action of free radicals and both…
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Highly Cited
1996
Highly Cited
1996
Neopterin and 7,8‐dihydroneopterin induce apoptosis in the rat alveolar epithelial cell line L2
W. Schobersberger
,
G. Hoffmann
,
+6 authors
D. Fuchs
FEBS letters
1996
Corpus ID: 42517965
The neopterin derivatives, neopterin and 7,8‐dihydroneopterin, modulate the cellular oxidant‐antioxidant balance as well as the…
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Highly Cited
1995
Highly Cited
1995
Effect of neopterin and 7,8‐dihydroneopterin on tumor necrosis factor‐α induced programmed cell death
G. Baier-Bitterlich
,
D. Fuchs
,
+6 authors
H. Wachter
FEBS letters
1995
Corpus ID: 30029754
Tumor necrosis factor‐α and the formation of reactive oxygen intermediates are central mediators of apoptosis. Recent data…
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Highly Cited
1995
Highly Cited
1995
7,8 Dihydroneopterin inhibits low density lipoprotein oxidation in vitro. Evidence that this macrophage secreted pteridine is an anti-oxidant.
S. Gieseg
,
G. Reibnegger
,
H. Wachter
,
H. Esterbauer
Free radical research
1995
Corpus ID: 42740639
Neopterin and its reduced form, 7,8 dihydroneopterin are pteridines released from macrophages and monocytes when stimulated with…
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