FAQ

Naproxen

Known as: Naproxène, (S)-2-(6-Methoxy-2-naphthyl)propanoic acid, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid 
A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
010020019682017

Related topics

Related topics

48 relations

Narrower (19)

AleveAnaproxHCT 3012Naprelan
(More)
Ankylosing spondylitisCYP1A2 protein, humanCYP2C9 protein, humanDegenerative polyarthritis
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Broader (4)

Anti-Inflammatory Agents, Non-SteroidalAntipyreticsTocolytic Agentsantiarthritic agent

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Naproxen
Pain
Inflammation
Drug Allergy
Rheumatoid Arthritis
Degenerative polyarthritis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
BACKGROUND Observational studies have shown reduced risk of Alzheimer dementia in users of nonsteroidal anti-inflammatory drugs… (More)
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Highly Cited
2007
Highly Cited
2007
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial.
OBJECTIVE To evaluate the efficacy and safety of naproxen and celecoxib for the primary prevention of Alzheimer disease (AD… (More)
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Highly Cited
2005
Highly Cited
2005
Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo.
BACKGROUND & AIMS Data indicate that cyclooxygenase-2-specific inhibitors cause less gastroduodenal mucosal damage than… (More)
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Highly Cited
2005
Highly Cited
2005
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
Alzheimer's disease (AD) involves amyloid beta (Abeta) accumulation, oxidative damage, and inflammation, and risk is reduced with… (More)
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Highly Cited
2004
Highly Cited
2004
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial.
BACKGROUND Cyclo-oxygenase 2 (COX2)-selective inhibitors should reduce ulcer complications compared with non-selective non… (More)
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Highly Cited
2004
Highly Cited
2004
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial.
BACKGROUND The potential for cyclo-oxygenase 2 (COX2)-selective inhibitors to increase the risk for myocardial infarction is… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.
CONTEXT Laboratory evidence that inflammatory mechanisms contribute to neuronal injury in Alzheimer disease (AD), along with… (More)
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Highly Cited
2003
Highly Cited
2003
Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters.
Although various single-concentration measurements of pharmaceuticals are available in the literature, detailed information on… (More)
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Highly Cited
2002
Highly Cited
2002
Association between naproxen use and protection against acute myocardial infarction.
BACKGROUND The association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and acute myocardial infarction (AMI… (More)
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Highly Cited
2000
Highly Cited
2000
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.
BACKGROUND Each year, clinical upper gastrointestinal events occur in 2 to 4 percent of patients who are taking nonselective… (More)
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