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NUDT1 gene

Known as: mutT human homolog 1, 7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-7,8-dihydroguanosine triphosphatase 
This gene plays a role in the hydrolysis of oxidized nucleotides.
National Institutes of Health

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Related topics

7 relations
8-oxodGTPaseHydrolysisNUDT1 protein, humanNUDT2 gene

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NUDT1 wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
Abstract 1189: MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1
OBJECTIVE: MicroRNAs (miRNAs) are emerging as important modulators in cellular pathways and appear to play a key role in… 
2007
2007
Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas.
2006
2006
Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array.
2004
2004
Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients
MYH, OGG1 and MTH1 are members of base excision repair (BER) families, and MYH germline mutations were recently identified in… 
Highly Cited
2002
Highly Cited
2002
Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator…
A total of 17 Nudix hydrolases were tested for their ability to hydrolyze 5-phosphoribosyl 1-pyrophosphate (PRPP). All 11 enzymes… 
2001
2001
Analysis of MTH1 gene function in mice with targeted mutagenesis.
2000
2000
Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress.
1997
1997
Biochemical and physicochemical characterization of normal and variant forms of human MTH1 protein with antimutagenic activity.
Highly Cited
1995
Highly Cited
1995
Mouse MTH1 Protein with 8-Oxo-7,8-dihydro-2′-deoxyguanosine 5′-Triphosphatase Activity That Prevents Transversion Mutation
8-Oxo-7,8-dihydro-2′-deoxyguanosine 5′-triphosphate (8-oxo-dGTP) is formed in the nucleotide pool of a cell during normal… 
Highly Cited
1995
Highly Cited
1995
cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides.
The enzyme, 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase (8-oxo-dGTPase), is present in various organisms and plays an… 
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