NUDT1 wt Allele

Known as: MTH1, Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 wt Allele 
Human NUDT1 wild-type allele is located within 7p22 and is approximately 9 kb in length. This allele, which encodes 7,8-dihydro-8-oxoguanine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNA and free dNTPs… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNAs (miRNAs) are emerging as important modulators in cellular pathways and they appear to play a key role in tumorigenesis… (More)
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Review
2007
Review
2007
Oxidative DNA lesions, such as 8-oxoguanine (8-oxoG), accumulate in nuclear and mitochondrial genomes during aging, and such… (More)
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Review
2007
Review
2007
Reactive oxygen species (ROS) are produced through normal cellular metabolism, and their formation is further enhanced by… (More)
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Highly Cited
2003
Highly Cited
2003
In budding yeast, HXT genes encoding hexose permeases are induced by glucose via a mechanism in which the F box protein Grr1… (More)
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2003
2003
MTH1 hydrolyzes oxidized purine nucleoside triphosphates such as 8-oxo-2'-deoxyguanosine 5'-triphosphate (8-oxo-dGTP) and 2… (More)
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Highly Cited
1999
Highly Cited
1999
The possibility that Escherichia coli MutT and human MTH1 (hMTH1) hydrolyze oxidized DNA precursors other than 8-hydroxy-dGTP (8… (More)
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Highly Cited
1999
Highly Cited
1999
The Std1 protein modulates the expression of glucose-regulated genes, but its exact molecular role in this process is unclear. A… (More)
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Highly Cited
1999
Highly Cited
1999
The objective of this study was to identify structural and functional factors which are predictors of peak pressure underneath… (More)
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Highly Cited
1997
Highly Cited
1997
Many theories have been advanced concerning the relationship between structure and function in the human foot, yet few of these… (More)
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