NU6102

Known as: O(6)-cyclohexylmethoxy-2-(4'-sulfamoylanilino)purine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2015
01220022015

Papers overview

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2016
2016
Progesterone receptor (PR) function is altered by cell signaling, but the mechanisms of kinase-specific regulation are not well… (More)
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2016
2016
Background:The phosphatidylinositol-3-kinase/mammalian target of rapamycin (PI3K/mTOR) pathway is commonly deregulated in human… (More)
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2011
2011
To facilitate the evaluation of CDK2 (cyclin-dependent kinase 2) as a cancer target, the in vitro and in vivo properties of… (More)
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2010
2010
Background:Cellular proliferation, driven by cyclin-dependent kinases (CDKs) and their cyclin partners, is deregulated in cancer… (More)
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2010
2010
The attenuated S(N)2 reactivity of the 2,2,2-trifluoroethyl group has been exploited for the synthesis of a series of 6… (More)
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2006
2006
Cyclin dependent kinases are a key family of kinases involved in cell cycle regulation and are an attractive target for cancer… (More)
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2005
2005
Inhibition of protein kinase activity is a focus of intense drug discovery efforts in several therapeutic areas. Major challenges… (More)
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2005
2005
Cyclin-dependent kinases (Cdks) play important roles in the regulation of the cell cycle. Their inhibitors have entered clinical… (More)
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2004
2004
The adenosine 5'-triphosphate (ATP) competitive cyclin-dependent kinase inhibitor O(6)-cyclohexylmethylguanine (NU2058, 1) has… (More)
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2002
2002
 
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