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NU6102

Known as: O(6)-cyclohexylmethoxy-2-(4'-sulfamoylanilino)purine 
National Institutes of Health

Papers overview

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2016
2016
Background:The phosphatidylinositol-3-kinase/mammalian target of rapamycin (PI3K/mTOR) pathway is commonly deregulated in human… 
2016
2016
Progesterone receptor (PR) function is altered by cell signaling, but the mechanisms of kinase-specific regulation are not well… 
Highly Cited
2015
Highly Cited
2015
2010
2010
The attenuated S(N)2 reactivity of the 2,2,2-trifluoroethyl group has been exploited for the synthesis of a series of 6… 
2010
2010
Background:Cellular proliferation, driven by cyclin-dependent kinases (CDKs) and their cyclin partners, is deregulated in cancer… 
2005
2005
AbstractCyclin-dependent kinases (Cdks) play important roles in the regulation of the cell cycle. Their inhibitors have entered… 
Highly Cited
2004
Highly Cited
2004
The adenosine 5'-triphosphate (ATP) competitive cyclin-dependent kinase inhibitor O(6)-cyclohexylmethylguanine (NU2058, 1) has…