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NTRK3 gene

Known as: neurotrophic receptor tyrosine kinase 3, NEUROTROPHIN 3 RECEPTOR, TYROSINE KINASE RECEPTOR C 
This gene plays a role in neuronal development and cellular differentiation. Mutations in the gene are associated with medulloblastomas, secretory… Expand
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Targeted inhibitors of neurotropic tyrosine kinases are highly effective in selected patients with gene fusions involving NTRK1… Expand
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Highly Cited
2016
Highly Cited
2016
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. The vast… Expand
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Highly Cited
2016
Highly Cited
2016
Here, we describe the dramatic response of a patient with an ETV6-NTRK3-driven mammary analogue secretory carcinoma to treatment… Expand
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Highly Cited
2016
Highly Cited
2016
AbstractBackgroundAbout 10–15% of adult, and most pediatric, gastrointestinal stromal tumors (GIST) lack mutations in KIT, PDGFRA… Expand
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2013
2013
The TrkC neurotrophin receptor belongs to the functional dependence receptor family, members of which share the ability to induce… Expand
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Highly Cited
2009
Highly Cited
2009
Genetic and functional data indicate that variation in the expression of the neurotrophin-3 receptor gene (NTRK3) may have an… Expand
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Highly Cited
2001
Highly Cited
2001
There is increasing interest in the potential role of the NTRK family of neurotrophin receptors in human neoplasia. These… Expand
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Highly Cited
2000
Highly Cited
2000
The congenital fibrosarcoma t(12;15)(p13;q25) rearrangement splices the ETV6 (TEL) gene on chromosome 12p13 in frame with the… Expand
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Highly Cited
1999
Highly Cited
1999
Chromosome translocations involving band 12p13 are known to be involved in a variety of hematologic malignancies, some of them… Expand
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Highly Cited
1998
Highly Cited
1998
Congenital (or infantile) fibrosarcoma (CFS) is a malignant tumour of f ibroblasts that occurs in patients aged two years or… Expand
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