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Neurotrophic Tyrosine Kinase Receptor Type 3

Known as: Kinase TRKC, Protein-Tyrosine, TRKC, Protein-Tyrosine Kinase, Receptor, Neurotrophic Tyrosine Kinase Type 3 
A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in nervous tissue and may play a role in mediating the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
With the FDA approval of larotrectinib, NTRK fusion assessment has recently become a standard part of management for patients… Expand
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Highly Cited
2018
Highly Cited
2018
Tropomyosin receptor kinase (Trk) inhibitors have shown high response rates in patients with tumors harboring NTRK fusions. We… Expand
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Highly Cited
2007
Highly Cited
2007
The TrkC/NT-3 receptor/ligand pair is believed to be part of the classic neurotrophic theory claiming that neuronal death occurs… Expand
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Highly Cited
2006
Highly Cited
2006
Neurotrophins play an essential role in mammalian development. Most of their functions have been attributed to activation of the… Expand
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Highly Cited
1999
Highly Cited
1999
Previous research has shown that corticospinal as well as rubrospinal neurons express the high-affinity trkB and trkC receptors… Expand
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Highly Cited
1998
Highly Cited
1998
We have previously described the expression of a functional full‐length trkC transcript for neurotrophin‐3 (NT‐3) receptor in… Expand
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Highly Cited
1997
Highly Cited
1997
Analysis of mice carrying targeted mutations in genes encoding neurotrophins and their signalling Trk receptors has provided… Expand
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Highly Cited
1994
Highly Cited
1994
The TrkB and TrkC receptor tyrosine kinases have been identified as high‐affinity receptors for the neurotrophic factors brain… Expand
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Highly Cited
1994
Highly Cited
1994
TrkC receptor isoforms have been identified by cDNA cloning and RT-PCR analysis of embryonic chick brain RNA. An N-terminal… Expand
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Highly Cited
1994
Highly Cited
1994
Neurotrophin-3 (NT-3) has mitogenic and neurogenic activities on distinct central and peripheral nervous system (CNS and PNS… Expand
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