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NTHL1 gene

Known as: NTHL1, OCTS3, Nth Endonuclease III-Like 1 (E. Coli) Gene 
This gene plays a role in nucleotide-excision DNA repair.
National Institutes of Health

Related topics

Related topics

5 relations
Base Excision RepairDNA RepairIron ChelationNTHL1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Contribution to colonic polyposis of recently proposed predisposing genes and assessment of the prevalence of NTHL1‐ and MSH3‐associated polyposes
Technological advances have allowed the identification of new adenomatous and serrated polyposis genes, and of several candidate… 
2017
2017
Delineating the Phenotypic Spectrum of the NTHL1‐Associated Polyposis
2015
2015
Biallelic NTHL1 Mutations in a Woman with Multiple Primary Tumors.
A patient is described with multiple cancers and compound heterozygous mutations in NTHL1, a recently described polyposis gene… 
2006
2006
Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array.
2004
2004
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe.
One of the most frequent lesions formed in cellular DNA are abasic (apurinic/apyrimidinic, AP) sites that are both cytotoxic and… 
Highly Cited
2003
Highly Cited
2003
The discovery of a new family of mammalian enzymes for repair of oxidatively damaged DNA, and its physiological implications.
Oxidatively damaged bases in the genome are likely to be responsible for mutations leading to sporadic carcinogenesis. Two… 
2002
2002
Response to oxidative stress caused by H2O2 in Saccharomyces cerevisiae mutants deficient in trehalase genes
Abstract. The role of trehalose as cell protector against oxidative stress induced by H2O2 has been studied in Saccharomyces… 
1998
1998
Stability of neutral trehalase during heat stress in Saccharomyces cerevisiae is dependent on the activity of the catalytic subunits of cAMP-dependent protein kinase, Tpk1 and Tpk2.
In Saccharomyces cerevisiae cAMP-dependent protein kinase (cAPK) is involved in nutrient sensing and growth regulation via the… 
Highly Cited
1997
Highly Cited
1997
Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein
Highly Cited
1995
Highly Cited
1995
Phenotypic features of trehalase mutants in Saccharomyces cerevisiae
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