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NTHL1 gene

Known as: NTHL1, OCTS3, Nth Endonuclease III-Like 1 (E. Coli) Gene 
This gene plays a role in nucleotide-excision DNA repair.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The genetic cause underlying the development of multiple colonic adenomas, the premalignant precursors of colorectal cancer (CRC… Expand
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Review
2007
Review
2007
Oxidatively induced DNA lesions have been implicated in the etiology of many diseases (including cancer) and in aging. Repair of… Expand
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Highly Cited
2005
Highly Cited
2005
The oxidatively induced DNA lesions 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 4,6-diamino-5-formamidopyrimidine… Expand
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Highly Cited
2003
Highly Cited
2003
Repair of oxidatively damaged bases in the genome via the base excision repair pathway is initiated with excision of these… Expand
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Highly Cited
2003
Highly Cited
2003
DNA damage mediated by reactive oxygen species generates miscoding and blocking lesions that may lead to mutations or cell death… Expand
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Highly Cited
2003
Highly Cited
2003
The relationship of trehalose metabolism to fungal virulence was explored in the rice blast fungus Magnaporthe grisea. To… Expand
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Highly Cited
2002
Highly Cited
2002
8-oxoguanine (8-oxoG), ring-opened purines (formamidopyrimidines or Fapys), and other oxidized DNA base lesions generated by… Expand
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Highly Cited
2002
Highly Cited
2002
Thymine glycol, a potentially lethal DNA lesion produced by reactive oxygen species, can be removed by DNA glycosylase… Expand
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Highly Cited
1999
Highly Cited
1999
A functional human homologue of Escherichia coli endonuclease III (Nth-Eco protein) has recently been cloned and characterized… Expand
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Highly Cited
1997
Highly Cited
1997
Repair of oxidative damage to DNA bases is essential to prevent mutations and cell death. Endonuclease III is the major DNA… Expand
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