Skip to search formSkip to main contentSkip to account menu

NS8593

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
TRPM7 activation potentiates SOCE in enamel cells but requires ORAI.
Highly Cited
2017
Highly Cited
2017
The TRPM7 channel kinase regulates store‐operated calcium entry
Pharmacological and molecular inhibition of transient receptor potential melastatin 7 (TRPM7) reduces store‐operated calcium… 
2017
2017
Store-operated Ca2+ entry is not required for fertilization-induced Ca2+ signaling in mouse eggs.
Highly Cited
2015
Highly Cited
2015
Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.
Highly Cited
2014
Highly Cited
2014
Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog
Background— Recent evidence points to functional Ca2+-dependent K+ (SK) channels in the heart that may govern atrial fibrillation… 
2014
2014
Physiological pathway of magnesium influx in rat ventricular myocytes.
2011
2011
Negative Gating Modulation by (R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) Depends on Residues in the Inner Pore Vestibule: Pharmacological Evidence of Deep-Pore Gating of…
Acting as a negative gating modulator, (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) shifts the apparent… 
Highly Cited
2011
Highly Cited
2011
The Duration of Pacing-induced Atrial Fibrillation Is Reduced in Vivo by Inhibition of Small Conductance Ca2+-activated K+ Channels
Atrial fibrillation (AF) is associated with increased morbidity and is in addition the most prevalent cardiac arrhythmia… 
Highly Cited
2008
Highly Cited
2008
Synthesis and Structure−Activity Relationship Studies of 2-(N-Substituted)-aminobenzimidazoles as Potent Negative Gating Modulators of Small Conductance Ca2+-Activated K+ Channels
Small conductance Ca2+-activated K+ channels (SK channels) participate in the control of neuronal excitability, in the shaping of… 
Highly Cited
2006
Highly Cited
2006
Inhibitory Gating Modulation of Small Conductance Ca2+-Activated K+ Channels by the Synthetic Compound (R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) Reduces…
SK channels are small conductance Ca2+-activated K+ channels important for the control of neuronal excitability, the fine tuning… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)