NQO1 gene

Known as: NAD(P)H Dehydrogenase, Quinone 1 Gene, NQO1, DHQU 
This gene is involved in drug/xenobiotic metabolism, biosynthetic processes and the prevention of cellular oxidative stress.
National Institutes of Health

Papers overview

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2014
2014
NQO1 (NAD(P)H: quinone oxidoreductase, also known as DT-diaphorase) plays a prominent role in maintaining cellular homeostasis… (More)
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2012
2012
Agents, such as β-lapachone, that target the redox enzyme, NAD(P)H:quinone oxidoreductase 1 (NQO1), to induce programmed necrosis… (More)
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Highly Cited
2008
Highly Cited
2008
NQO1 guards against oxidative stress and carcinogenesis and stabilizes p53. We find that a homozygous common missense variant… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Exposure to anthracyclines as part of cancer therapy has been associated with the development of congestive heart… (More)
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2007
2007
Estrogen ortho-quinones have been implicated as ultimate carcinogenic metabolites of estrogens. The present conclusion that… (More)
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Highly Cited
2001
Highly Cited
2001
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that utilizes NAD(P)H as an electron donor, catalyzing the two-electron… (More)
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Review
1999
Review
1999
NAD(P)H:quinone oxidoreductase 1 (NQO1; EC 1.6.99.2), originally called DT-diaphorase (1), is an enzyme that has attracted… (More)
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1999
1999
NAD(P)H:quinone oxidoreductase 1 (NQO1), a redox-regulated flavoenzyme, plays a central role in monitoring cellular redox state… (More)
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1996
1996
Sir NQO1 has attracted considerable attention owing to its ability to deactivate a broad range of xenobiotics while activating… (More)
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1991
1991
DT diaphorase (NAD(P)H dehydrogenase (quinone), EC 1.6.99.2) isolated from Walker 256 rat carcinoma cells can convert CB 1954 (5… (More)
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