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NQO1 gene

Known as: NAD(P)H Dehydrogenase, Quinone 1 Gene, NQO1, DHQU 
This gene is involved in drug/xenobiotic metabolism, biosynthetic processes and the prevention of cellular oxidative stress.
National Institutes of Health

Related topics

Related topics

7 relations
Metabolic Detoxication, DrugNAD(P)H Dehydrogenase (Quinone)NAD(P)H dehydrogenase (quinone) 1, humanOxidation-Reduction

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NQO1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
An HBT-based fluorescent dye with enhanced quantum yield in water system and its application for constructing NQO1 fluorescent probe.
2016
2016
Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands
Protein dynamics is essential to understand protein function and stability, even though is rarely investigated as the origin of… 
2016
2016
NQO1 Deficiency Leads Enhanced Autophagy in Cisplatin-Induced Acute Kidney Injury Through the AMPK/TSC2/mTOR Signaling Pathway.
AIMS Recent studies have revealed that autophagy is induced under various disease conditions; however, the role of autophagy in… 
2011
2011
Persistent expression of Nqo1 by p62-mediated Nrf2 activation facilitates p53-dependent mitotic catastrophe.
2006
2006
In silico identification and biochemical characterization of novel inhibitors of NQO1.
2003
2003
The role of quinone reductase (NQO1) and quinone chemistry in quercetin cytotoxicity.
Highly Cited
1991
Highly Cited
1991
The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide)
Highly Cited
1991
Highly Cited
1991
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids.
A panel of 18 rat x mouse somatic cell hybrid clones segregating individual rat chromosomes in different combinations was used to… 
Highly Cited
1988
Highly Cited
1988
Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.
Highly Cited
1986
Highly Cited
1986
NAD(P)H:menadione oxidoreductase. Novel purification of enzyme cDNA and complete amino acid sequence, and gene regulation.
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