NOD2 wt Allele

Known as: CD, Nucleotide-Binding Oligomerization Domain Containing 2 wt Allele, NLRC2 
Human NOD2 wild-type allele is located in the vicinity of 16q21 and is approximately 36 kb in length. This allele, which encodes nucleotide-binding… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND & AIMS The ability to identify children with CD who are at highest risk for rapid progression from uncomplicated to… (More)
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Highly Cited
2007
Highly Cited
2007
We present a genome-wide association study of ileal Crohn disease and two independent replication studies that identify several… (More)
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Highly Cited
2005
Highly Cited
2005
Both NOD2 (CARD15) alleles are mutated in roughly 15% of patients with Crohn's disease, but functional effects are unclear. We… (More)
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Highly Cited
2004
Highly Cited
2004
Crohn disease is a chronic, inflammatory disease of the gastrointestinal tract. A locus of ∼250 kb at 5q31 (IBD5) was previously… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Mutations in NOD2, a putative intracellular receptor for bacterial peptidoglycans, are associated with a subset of… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Variants of the caspase activating recruitment domain 15/nucleotide oligomerisation domain 2 (CARD15/NOD2) gene have… (More)
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Highly Cited
2003
Highly Cited
2003
  • Arie, C -, LAIRE, ILLEVAL
  • 2003
A demand for behavioral norms arises when members of a group have individual incentives to take actions that reduce the group's… (More)
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Highly Cited
2003
Highly Cited
2003
Current debate focuses on the relevance of linkage disequilibrium (LD), ethnicity and underlying haplotype structure to the… (More)
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Highly Cited
2001
Highly Cited
2001
We have identified three missense mutations in the nucleotide-binding domain (NBD) of CARD15/NOD2 in four French and German… (More)
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Highly Cited
1998
Highly Cited
1998
The idiopathic inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis (UC), are chronic, frequently disabling… (More)
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