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NOD2 wt Allele

Known as: CD, Nucleotide-Binding Oligomerization Domain Containing 2 wt Allele, NLRC2 
Human NOD2 wild-type allele is located in the vicinity of 16q21 and is approximately 36 kb in length. This allele, which encodes nucleotide-binding… 
National Institutes of Health

Related topics

Related topics

7 relations
16q21ApoptosisCTLA4 geneCaspase-Dependent Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population
Background: Although many genetic variants are identified in association with Crohn's disease (CD), CARD15, IL23R, and ATG16L1… 
2007
2007
Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn’s disease but also ulcerative colitis
Background  A recent study reported that a non‐synonymous single nucleotide polymorphism (rs11209026, p.Arg381Gln) located in the… 
Highly Cited
2006
Highly Cited
2006
Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations
The first gene associated with Crohn disease (CD) has been identified as CARD15 (16q12). Three variants, R702W, G908R and… 
Review
2005
Review
2005
CARD15 Mutations Are Rare in Swedish Pediatric Crohn Disease
Background: An association between mutations in a gene involved in bacterial recognition by monocytes, CARD15/NOD2 and Crohn… 
Highly Cited
2004
Highly Cited
2004
Transmission of CARD15 (NOD2) Variants Within Families of Patients with Inflammatory Bowel Disease
OBJECTIVES:Three single nucleotide polymorphisms (SNPs) in CARD15 have been independently associated with Crohn's disease (CD… 
Highly Cited
2003
Highly Cited
2003
CARD15 Genotype and Phenotype Analysis in 55 Pediatric Patients With Crohn Disease From Saxony, Germany
Objectives Crohn disease is a chronic inflammatory bowel disorder that is caused by environmental and genetic factors. Mutations… 
2003
2003
Association between mutations in the CARD15 (NOD2) gene and Crohn's disease in Israeli Jewish patients
Ulcerative colitis (UC) and Crohn's disease (CD) are heterogeneous disorders characterized by chronic intestinal inflammation… 
Highly Cited
2002
Highly Cited
2002
CARD15 gene and the classification of Crohn's disease
Abstract. An insertion mutation at nucleotide 3020 (3020insC) in the CARD15 gene, originally reported as NOD2, has been strongly… 
Highly Cited
2002
Highly Cited
2002
Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6
Inflammatory bowel disease (IBD) is a multifactorial disorder, with both genetic and environmental factors contributing to the… 
Highly Cited
2001
Highly Cited
2001
Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3)
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine, commonly diagnosed as either ulcerative… 
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