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NME2 gene

Known as: NM23B, NONMETASTATIC PROTEIN 23B, NM23H2 
National Institutes of Health

Related topics

Related topics

1 relation
Nucleoside Diphosphate Kinase B

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression
Regulatory influence of the G-quadruplex or G4 motif present within the nuclease hypersensitive element (NHE) in the promoter of… 
Highly Cited
2000
Highly Cited
2000
TIP30 has an intrinsic kinase activity required for up‐regulation of a subset of apoptotic genes
CC3 is a metastasis suppressor that inhibits metastasis of the variant small cell lung carcinoma (v‐SCLC) by predisposing cells… 
Highly Cited
2000
Highly Cited
2000
Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function.
NM23/NDP kinases play an important role in development and cancer but their biological function is unknown, despite an intriguing… 
Highly Cited
1999
Highly Cited
1999
Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent…
The metastasis suppressor activity of nm23/nucleoside diphosphate (NDP) kinase was assessed using human oral squamous cell… 
Highly Cited
1997
Highly Cited
1997
nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13
Abstract A novel human nm23/nucleoside diphosphate (NDP) kinase gene, called nm23-H4, was identified by screening a human stomach… 
Highly Cited
1995
Highly Cited
1995
The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.
The 2.8 A resolution X-ray structure of NM23-H2 has been determined by molecular replacement using the structure of Myxococcus… 
Highly Cited
1995
Highly Cited
1995
Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line.
A series of sublines of a murine melanoma B16 of C57BL/6 origin were established and examined regarding their metastatic capacity… 
Highly Cited
1994
Highly Cited
1994
Nucleoside diphosphate kinase enzyme activity of NM23-H2/PuF is not required for its DNA binding and in vitro transcriptional functions.
Highly Cited
1994
Highly Cited
1994
Expression of human nm23‐H1 and nm23‐H2 proteins in hepatocellular carcinoma
Background. The expression of nm23‐H1 and nm23‐H2 proteins in 25 hepatocellular carcinomas was studied immunohistochemically. 
Highly Cited
1993
Highly Cited
1993
Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas.
Reduced expression of nm23 RNAs/proteins has been associated previously with high tumor metastatic potential. In contrast, we… 
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