• Publications
  • Influence
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
TLDR
The observation of bi-allelic alterations of hSNF5/INI1 in MRTs suggests that loss-of-function mutations of h snf5/inI1 contribute to oncogenesis, and the most frequently deleted part of chromosome 22q11.2 is mapped. Expand
RhoGDI-3 Is a New GDP Dissociation Inhibitor (GDI)
TLDR
This work has reported that the transient expression of the endogenous RhoB protein is regulated during the cell cycle, contrasting with the permanent RhoA protein expression, and identified a new mouse Rho GDP dissociation inhibitor, referenced as RhoGDI-3. Expand
hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors.
TLDR
Molecular cytogenetic data obtained in 12 cell lines harboring hSNF5/INI1 mutations and/or deletions in relation to the molecular genetic analysis using polymorphic markers extended to both extremities of chromosome 22q show mitotic recombination occurring in the proximal part of chromosomes 22q, and nondisjunction/duplication, highly suspected in two cases. Expand
nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13
TLDR
A novel human nm23/nucleoside diphosphate (NDP) kinase gene, called nm23-H4, was identified by screening a human stomach cDNA library with a probe generated by amplification by reverse transcription-polymerase chain reaction, strongly suggesting that Nm23- H4 possesses NDP kinase activity. Expand
Chromosome mapping of the human RAS-related RAP1A, RAP1B, and RAP2 genes to chromosomes 1p12----p13, 12q14, and 13q34, respectively.
TLDR
Using the complete cDNAs or parts thereof as probes, each RAP gene has been localized on human chromosomes by in situ hybridization and has been assigned to chromosome bands 1p12----p13, 12q14, and 13q34, respectively. Expand
Localization of the human luteinizing hormone/choriogonadotropin receptor gene (LHCGR) to chromosome 2p21.
Probes corresponding to human and porcine LH (luteinizing hormone) receptor cDNA were used for in situ hybridization to human chromosomes. This allowed us to assign the LH receptor gene to chromosomeExpand
The chromosomal localization of the human follicle-stimulating hormone receptor gene (FSHR) on 2p21-p16 is similar to that of the luteinizing hormone receptor gene.
Two cDNA probes (5' and 3' region) corresponding to the human follicle-stimulating hormone receptor gene (FSHR) were used for chromosomal localization by in situ hybridization. The localizationExpand
Assignment of the human thyroid stimulating hormone receptor (TSHR) gene to chromosome 14q31.
In situ hybridization experiments on human chromosomes were performed using probes corresponding to the 5' and 3' parts of human TSHR cDNA. Both probes allowed a regional localization on chromosomeExpand
Reactivity of histiocytosis X cells with monoclonal antibodies.
TLDR
The data confirm the close relationship existing between histiocytic X cells, Langerhans cells and dendritic cells, and suggest to consider the T6 antigen either as an early differentiation marker of thymocytes or as a functional marker of Mononuclear Phagocyte System subpopulations. Expand
Chromosomal localization of two human zinc finger protein genes, ZNF24 (KOX17) and ZNF29 (KOX26), to 18q12 and 17p13-p12, respectively.
TLDR
Two members of the zinc finger Krüppel family, ZNF24 and ZNF29, have been localized by somatic cell hybrid analysis and in situ chromosomal hybridization to human chromosomes 18q12 and 17p13-p12, suggesting that a zinc finger gene complex is located on human chromosome 17p. Expand
...
1
2
3
4
5
...