NKX2-1 gene

Known as: NK2.1, MOUSE, HOMOLOG OF, TITF1, NKX2A 
This gene plays a role in thyroid gene transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
0102019762018

Papers overview

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Highly Cited
2012
Highly Cited
2012
We and others previously identified NKX2-1, also known as TITF1 and TTF-1, as a lineage-survival oncogene in lung adenocarcinomas… (More)
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2012
2012
Mucinous adenocarcinoma of the lung is a subtype of highly invasive pulmonary tumors and is associated with decreased or absent… (More)
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Highly Cited
2011
Highly Cited
2011
To identify oncogenic pathways in T cell acute lymphoblastic leukemia (T-ALL), we combined expression profiling of 117 pediatric… (More)
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Highly Cited
2008
Highly Cited
2008
A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level… (More)
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Highly Cited
2007
Highly Cited
2007
Somatic alterations in cellular DNA underlie almost all human cancers. The prospect of targeted therapies and the development of… (More)
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Highly Cited
2005
Highly Cited
2005
Thyroid dysgenesis (TD) is responsible for most cases of congenital hypothyroidism, a condition that affects about one in 4000… (More)
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Highly Cited
2004
Highly Cited
2004
Telomere maintenance has been implicated in cancer and ageing, and requires cooperation between a multitude of telomeric factors… (More)
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Highly Cited
2002
Highly Cited
2002
The occurrence of neurological symptoms and developmental delay in patients affected by congenital hypothyroidism (CH) has been… (More)
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Highly Cited
1998
Highly Cited
1998
Targeted disruption of the homeobox gene T/ebp (Nkx2.1, Ttf1, Titf1) in mice results in ablation of the pituitary. Paradoxically… (More)
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Highly Cited
1992
Highly Cited
1992
A 420-bp fragment from the 5' end of the rat thyroperoxidase (TPO) gene was fused to a luciferase reporter and shown to direct… (More)
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