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Avian Malaria Deaths in Parrots, Europe
- P. Olias, Maria Wegelin, W. Zenker, S. Freter, A. Gruber, R. Klopfleisch
- Medicine, Biology
- Emerging infectious diseases
- 1 May 2011
A phylogenetic comparison of the mitochondrial cytochrome b gene derived from protozoan cyst-like structures with known sequences of avian hematozoa found 99%–100% homology of parasites from both outbreaks with the avian malaria parasites (Haemoproteus spp.) of European songbirds. Expand
Pathology of Natural Infections by H5N1 Highly Pathogenic Avian Influenza Virus in Mute (Cygnus olor) and Whooper (Cygnus cygnus) Swans
The infection of the central nervous system supports the view that the neurotropism of H5N1 HPAIV leads to nervous disturbances with loss of orientation and more investigations are necessary to clarify the mechanisms of the final circulatory failure, lung edema, and rapid death of the swans. Expand
Functional Analysis of the Pseudorabies Virus UL51 Protein
Both conserved tegument proteins, either singly or in combination, are involved in virion morphogenesis in the cytoplasm but are not essential for viral replication in vitro and in vivo. Expand
Commensal Akkermansia muciniphila Exacerbates Gut Inflammation in Salmonella Typhimurium-Infected Gnotobiotic Mice
Results indicate that A. muciniphila exacerbates S. Typhimurium-induced intestinal inflammation by its ability to disturb host mucus homeostasis. Expand
The pathology of the foreign body reaction against biomaterials.
- R. Klopfleisch, F. Jung
- Materials Science, Medicine
- Journal of biomedical materials research. Part A
- 1 March 2017
This review is focused on the current knowledge on the general mechanisms of the FBR against biomaterials and the influence of biomaterial surface topography and chemical and physical features on the quality and quantity of the reaction. Expand
Macrophage reaction against biomaterials in the mouse model - Phenotypes, functions and markers.
- R. Klopfleisch
- Biology, Medicine
- Acta biomaterialia
- 1 October 2016
This review gives a comprehensive overview on the taxonomy of the currently known macrophage subtypes, with a lack on a good summary on the current taxonomy, functions and phenotypes of macrophages in my recent projects on the biocompatibility of biomaterials in the mouse model. Expand
Molecular Carcinogenesis of Canine Mammary Tumors
- R. Klopfleisch, Henrik P von Euler, G. Sarli, S. Pinho, F. Gärtner, A. Gruber
- Biology, Medicine
- Veterinary pathology
- 1 January 2011
Current knowledge on the molecular carcinogenesis of CMT is summarized, including the role of specific oncogenes, tumor suppressors, regulators of apoptosis and DNA repair, proliferation indices, adhesion molecules, circulating tumor cells, and mediators of angiogenesis in CMT progression and clinical behavior. Expand
Excavation of a buried treasure--DNA, mRNA, miRNA and protein analysis in formalin fixed, paraffin embedded tissues.
This review gives an overview on current potentials and limitations of the quantification of DNA, miRNA, mRNA and the proteome in FFPE tissue samples. Expand
Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition.
CD-TREAT replicates EEN changes in the microbiome, decreases gut inflammation, is well tolerated, and is potentially effective in patients with active CD. Expand
Encephalitis in a stone marten (Martes foina) after natural infection with highly pathogenic avian influenza virus subtype H5N1.
- R. Klopfleisch, P. Wolf, +5 authors J. Teifke
- Medicine, Biology
- Journal of comparative pathology
- 1 August 2007
The microscopical lesions and viral antigen distribution in this stone marten differs from that recently described for cats naturally and experimentally infected with the same virus subtype, and is the first report of natural infection of a mustelid with HPAIV H5N1. Expand