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NKT-01

National Institutes of Health

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2 relations

Broader (2)

gusperimusgusperimus trihydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Phase I study of NKT-01
A phase I study of NKT-01 (deoxyspergualin), which is a derivative of an antitumor antibiotic, spergualin, was performed by a… 
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Review
1996
Review
1996
15-Deoxyspergualin: a newly developed immunosuppressive agent and its mechanism of action and clinical effect: a review. Japan Collaborative Transplant Study Group for NKT-01.
  • H. Amemiya
  • Artificial organs
  • 1996
  • Corpus ID: 33774306
15-Deoxyspargualin (DSG) is a synthetic analogue of spergualin isolated from the culture filtrate of Bacillus laterosporus. It… 
1991
1991
Deoxyspergualin in lethal murine graft-versus-host disease.
The beneficial effect of deoxyspergualin (DSG, NKT-01) on lethal graft-versus-host disease in mice has been studied in a major… 
1991
1991
Antitumor spectrum of deoxyspergualin and its lack of cross-resistance to other antitumor agents.
Antitumor activities of 15-deoxyspergualin (NKT-01), an analogue of spergualin (SGL), were examined in cultured tumor cells… 
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1991
1991
Cytostatic Effect of Deoxyspergualin on a Murine Leukemia Cell Line L1210
The mode of antiproliferative action of deoxyspergualin (NKT‐01) was examined. The growth‐inhibitory effect on a murine leukemia… 
Highly Cited
1990
Highly Cited
1990
Deoxyspergualin directly suppresses antibody formation in vivo and in vitro.
The effect of deoxyspergualin (DSG, NKT-01) on humoral immunity was investigated both in vitro and in vivo. DSG inhibited the… 
1988
1988
Reversal of acute rejection episodes by deoxyspergualin (NKT-01) in dogs receiving renal allografts.
: Rokitamycin (RKM) dry syrup, a newly developed macrolide antibiotic, was administered to children with ages between 6 months… 
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1988
1988
In vivo effects of deoxyspergualin (NKT-01) on lymphocyte activation in response to alloantigens.
We studied the effects of deoxyspergualin (NKT-01) on the events of lymphocyte activation in vivo by inoculating mice in the… 
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1988
1988
Biological activities of deoxyspergualin in autoimmune disease mice.
An assessment of the prophylactic and ameliorative effects of deoxyspergualin (NKT-01), an immunosuppressive agent, was carried… 
1988
1988
The antiproliferative action of deoxyspergualin is different from that induced by amine oxidase.
The amine oxidase activities contained in calf serum and human serum were detected at levels of 90.8 and less than 0.1 nmol O2… 
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