Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

gusperimus

Known as: 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione, Heptanamide, 7-((Aminoiminomethyl)amino)-N-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-, 15-Deoxyspergualin 
A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
T-cell depletion facilitates reduced immunosuppression following organ transplantation and has been suggested to be pro-tolerant… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Stabilized plasmid lipid particles (SPLP) consist of a single copy of DNA surrounded by a lipid bilayer. The particles are small… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The molecular chaperone and cytoprotective activities of the Hsp70 and Hsp40 chaperones represent therapeutic targets for human… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • table II
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
An active role of T regulatory cells (Treg) and tolerogenic dendritic cells (Tol-DC) is believed important for the induction and… Expand
  • figure 2
  • figure 1
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The studies reported here bear on the events in the cytosol that lead to trafficking of peptides during antigen processing and… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A new concept for the construction of locking-free finite elements for bending of shear deformable plates and shells, called DSG… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
ObjectiveTo assess the pharmacokinetics of etonogestrel and ethinylestradiol released from a novel combined contraceptive vaginal… Expand
Is this relevant?
Review
1998
Review
1998
Nuclear factor kappa B (NF-kappa B) is an ubiquitous rapid response transcription factor in cells involved in immune and… Expand
Is this relevant?
Review
1998
Review
1998
Successful expression of polypeptide gene products requires transcription machinery to generate messenger ribonucleic acids and… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?