gusperimus

Known as: 1-amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione, Heptanamide, 7-((aminoiminomethyl)amino)-N-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-, 15-deoxyspergualin 
A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
0204019822017

Papers overview

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2008
2008
A group of patients with type 2 diabetes mellitus (T2DM) and body mass index (BMI) 20–34 kg/m2 were submitted to laparoscopic… (More)
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2007
2007
Induction of hematopoietic chimerism and subsequent donor-specific immune tolerance via bone marrow transplantation is an ideal… (More)
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Highly Cited
2005
Highly Cited
2005
T-cell depletion facilitates reduced immunosuppression following organ transplantation and has been suggested to be pro-tolerant… (More)
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Highly Cited
2003
Highly Cited
2003
Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal… (More)
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Highly Cited
2003
Highly Cited
2003
The combination of cyclophosphamide (CYC) and oral corticosteroids is effective in the majority of patients with antineutrophil… (More)
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2002
2002
The CFTR (cystic fibrosis transmembrane conductance regulator) gene, defective in cystic fibrosis, codes for a polytopic apical… (More)
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2000
2000
BACKGROUND AND PURPOSE The time courses of total creatine (Cr), N-acetylaspartate (NAA), choline (Cho), and myo-inositol have not… (More)
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1996
1996
The in vivo administration of adenovirus vectors frequently elicits a neutralizing antibody response which eliminates or… (More)
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1993
1993
Islet transplantation has been slow to develop as a therapy for type I diabetes mellitus. Conventional immunosuppression does not… (More)
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Highly Cited
1992
Highly Cited
1992
Deoxyspergualin (DSG) is a potent immunosuppressant whose mechanism of action remains unknown. To elucidate its mechanism of… (More)
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