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NFAT5 gene

Known as: nuclear factor of activated T-cells 5, tonicity-responsive, TONEBP, NFAT5 
This gene is involved in gene transcription and cellular stress responses.
National Institutes of Health

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Related topics

8 relations
Cellular Stress ResponseHomo sapiensNFAT Transcription Factor 5NFAT5 protein, human

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NFAT5 wt Allele

Papers overview

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2015
2015
NFAT5 Is Up-Regulated by Hypoxia: Possible Implications in Preeclampsia and Intrauterine Growth Restriction1
ABSTRACT During gestation, low oxygen environment is a major determinant of early placentation process, while persistent… 
Highly Cited
2014
Highly Cited
2014
MiR-568 inhibits the activation and function of CD4⁺ T cells and Treg cells by targeting NFAT5.
CD4(+) T cells play critical roles in orchestrating adaptive immune responses. Their activation and proliferation are critical… 
2014
2014
Increased NFAT5 expression stimulates transcription of Hsp70 in preeclamptic placentas.
2011
2011
Tumor necrosis factor-related genes and colon and rectal cancer.
Tumor necrosis factor-α (TNF) is a promoter of inflammation. Genes in the TNF pathway include tumor necrosis factor receptor… 
2009
2009
Automatic Processing of EEG-EOG-EMG Artifacts in Sleep Stage Classification
In this paper, we present a series of algorithms for dealing with artifacts in electroencephalograms (EEG), electrooculograms… 
2008
2008
Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking*
The osmotic response element-binding protein (OREBP), also known as tonicity enhancer-binding protein (TonEBP) or NFAT5, is the… 
2007
2007
Discovery of Osmosensitive Transcriptional Regulation of Human Cytochrome P450 3As by the Tonicity-Responsive Enhancer Binding Protein (Nuclear Factor of Activated T Cells 5)
We report the discovery of an osmosensitive transcriptional control of human CYP3A4, CYP3A7, and CYP3A5. Ambient hypertonicity… 
Highly Cited
2005
Highly Cited
2005
High NaCl increases TonEBP/OREBP mRNA and protein by stabilizing its mRNA.
Hypertonicity increases mRNA and protein abundance of the transcription factor tonicity-responsive enhancer/osmotic response… 
2004
2004
The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in response to oxygen tension
An oxygen responsive transcription factor regulating human glutathione peroxidase gene (GPx) through two oxygen responsive… 
2002
2002
Dimerization is required for phosphorylation and DNA binding of TonEBP/NFAT5.
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