Skip to search formSkip to main contentSkip to account menu

NF-Kappa-B Essential Modulator

Known as: IKK-gamma, Ikb Kinase-Associated Protein 1, Ikb Kinase Subunit Gamma 
NF-kappa-B essential modulator (419 aa, ~48 kDa) is encoded by the human IKBKG gene. This protein plays a role in the mediation of signal… 
National Institutes of Health

Related topics

Related topics

6 relations
IKBKG geneIKBKG wt AlleleIkappaB kinaseImmune response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation*
The IκB kinase (IKK) complex acts as a gatekeeper of canonical NF-κB signaling in response to upstream stimulation. IKK… 
2011
2011
SYT-SSX1 (Synovial Sarcoma Translocated) Regulates PIASy Ligase Activity to Cause Overexpression of NCOA3 Protein*
Chromosomal translocations are a major source of genetic abnormalities causally linked to certain malignancies. Synovial sarcoma… 
2009
2009
Periodic, Partial Inhibition of IκB Kinase β-Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis
We have previously shown that inhibitors of IκB kinase β (IKKβ), including 4(2′-aminoethyl)amino-1,8-dimethylimidazo(1,2-a… 
Review
2009
Review
2009
[Involvement of LUBAC-mediated linear polyubiquitination of NEMO in NF-kappaB activation].
2007
2007
Nemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development
ABSTRACT The development of anterior neural structure in Xenopus laevis requires the inhibition of bone morphogenic protein 4 and… 
Review
2006
Review
2006
Extending the nuclear roles of IkappaB kinase subunits.
The transcription factor NF-kappaB plays a key role in a wide variety of cellular processes such as innate and adaptive immunity… 
2004
2004
Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator.
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-associated guanylate kinase-like… 
2002
2002
Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation.
The IkappaB kinase (IKK) complex includes the catalytic components IKKalpha and IKKbeta in addition to the scaffold protein… 
2001
2001
Human-mouse comparative sequence analysis of the NEMO gene reveals an alternative promoter within the neighboring G6PD gene.
2001
2001
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex.
IKKgamma/NEMO is a protein that is critical for the assembly of the high molecular weight IkappaB kinase (IKK) complex. To… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)