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NF-Kappa-B Essential Modulator
Known as:
IKK-gamma
, Ikb Kinase-Associated Protein 1
, Ikb Kinase Subunit Gamma
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NF-kappa-B essential modulator (419 aa, ~48 kDa) is encoded by the human IKBKG gene. This protein plays a role in the mediation of signal…
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National Institutes of Health
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Related topics
Related topics
6 relations
IKBKG gene
IKBKG wt Allele
IkappaB kinase
Immune response
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation*
K. Hadian
,
Richard A. Griesbach
,
+6 authors
D. Krappmann
Journal of Biological Chemistry
2011
Corpus ID: 3114104
The IκB kinase (IKK) complex acts as a gatekeeper of canonical NF-κB signaling in response to upstream stimulation. IKK…
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2011
2011
SYT-SSX1 (Synovial Sarcoma Translocated) Regulates PIASy Ligase Activity to Cause Overexpression of NCOA3 Protein*
Yin Sun
,
J. Perera
,
B. Rubin
,
Jiaoti Huang
Journal of Biological Chemistry
2011
Corpus ID: 25315341
Chromosomal translocations are a major source of genetic abnormalities causally linked to certain malignancies. Synovial sarcoma…
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2009
2009
Periodic, Partial Inhibition of IκB Kinase β-Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis
Kathleen M. Gillooly
,
M. Pattoli
,
+19 authors
J. Burke
Journal of Pharmacology and Experimental…
2009
Corpus ID: 2290793
We have previously shown that inhibitors of IκB kinase β (IKKβ), including 4(2′-aminoethyl)amino-1,8-dimethylimidazo(1,2-a…
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Review
2009
Review
2009
[Involvement of LUBAC-mediated linear polyubiquitination of NEMO in NF-kappaB activation].
F. Tokunaga
,
K. Iwai
Tanpakushitsu kakusan koso. Protein, nucleic acid…
2009
Corpus ID: 37185962
2007
2007
Nemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development
Kiyotoshi Satoh
,
J. Ohnishi
,
+4 authors
H. Shibuya
Molecular and Cellular Biology
2007
Corpus ID: 17250573
ABSTRACT The development of anterior neural structure in Xenopus laevis requires the inhibition of bone morphogenic protein 4 and…
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Review
2006
Review
2006
Extending the nuclear roles of IkappaB kinase subunits.
G. Gloire
,
E. Dejardin
,
J. Piette
Biochemical Pharmacology
2006
Corpus ID: 27278305
The transcription factor NF-kappaB plays a key role in a wide variety of cellular processes such as innate and adaptive immunity…
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2004
2004
Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator.
R. Stilo
,
D. Liguoro
,
+4 authors
P. Vito
Journal of Biological Chemistry
2004
Corpus ID: 25921904
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-associated guanylate kinase-like…
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2002
2002
Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation.
S. Prajapati
,
R. Gaynor
Journal of Biological Chemistry
2002
Corpus ID: 25727771
The IkappaB kinase (IKK) complex includes the catalytic components IKKalpha and IKKbeta in addition to the scaffold protein…
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2001
2001
Human-mouse comparative sequence analysis of the NEMO gene reveals an alternative promoter within the neighboring G6PD gene.
P. Galgóczy
,
A. Rosenthal
,
M. Platzer
Gene
2001
Corpus ID: 29244277
2001
2001
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex.
X. H. Li
,
X. Fang
,
R. Gaynor
Journal of Biological Chemistry
2001
Corpus ID: 29245911
IKKgamma/NEMO is a protein that is critical for the assembly of the high molecular weight IkappaB kinase (IKK) complex. To…
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