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IKBKG gene

Known as: IKK-GAMMA, FIP3, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 
This gene plays a role in the regulation of signal transduction.
National Institutes of Health

Related topics

Related topics

5 relations
IKBKE geneImmune responseNF-Kappa-B Essential ModulatorSignal Transduction

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IKBKG wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
MicroRNA-107 Targets IKBKG and Sensitizes A549 Cells to Parthenolide
Background/Aim: Patients with advanced non-small cell lung cancer (NSCLC) frequently face a dismal prognosis because of lack of… 
2014
2014
Duplication at Xq28 involving IKBKG is associated with progressive macrocephaly, recurrent infections, ectodermal dysplasia, benign tumors, and neuropathy
Duplications on Xq28 are common, although quite variable in size, but usually include the MECP2 gene. Here, we present a patient… 
2013
2013
First IKBKG gene mutation study in Serbian incontinentia pigmenti patients.
INTRODUCTION Incontinentia pigmenti (IP) is a rare X-linked dominant genodermatosis. Mutations of the IKBKG gene are the only… 
2011
2011
Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen‐activated protein kinase activity
The covalent attachment of lysine 63‐linked polyubiquitin to the zinc‐finger domain of IKBKG/NEMO (also known as IKKγ) is… 
2010
2010
The Common NF-κB Essential Modulator (NEMO) Gene Rearrangement in Korean Patients with Incontinentia Pigmenti
Incontinentia pigmenti (IP) is a rare X-linked dominant disorder characterized by highly variable abnormalities of the skin, eyes… 
2009
2009
Microdeletion / Duplication at the Xq 28 IP Locus Causes a De Novo IKBKG / NEMO / IKKgamma exon 4 _ 10 Deletion in Families with Incontinentia Pigmenti
The Incontinentia Pigmenti (IP) locus contains the IKBKG/NEMO/IKKgamma gene and its truncated pseudogene copy, IKBKGP/deltaNEMO… 
Highly Cited
2007
Highly Cited
2007
Molecular characterization of Rab11-FIP3 binding to ARF GTPases.
Review
2007
Review
2007
Incontinentia pigmenti in a newborn with a novel nonsense mutation in the NEMO gene
congenital mesodermal abnormalities characterized by portwine stain, venous varicosities, and hypertrophy of soft tissue and/or… 
2007
2007
Bevacizumab: a compassionate way of doing business?
abnormalities in the peripheral retina. The similarities of avascularization in both patients suggest that NEMO may be involved… 
2001
2001
Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity.
FIP-3 (NEMO/IKKgamma) is an essential modulator of the activity of NF-kappaB by mechanisms that include alterations in the… 
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