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IKBKG gene

Known as: IKK-GAMMA, FIP3, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 
This gene plays a role in the regulation of signal transduction.
National Institutes of Health

Related topics

Related topics

5 relations
IKBKE geneImmune responseNF-Kappa-B Essential ModulatorSignal Transduction

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IKBKG wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Incontinentia pigmenti (Bloch-Sulzberger syndrome).
2015
2015
Structure of Rab11–FIP3–Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11
The small GTPase Rab11 and its effectors FIP3 and Rabin8 are essential to membrane-trafficking pathways required for cytokinesis… 
Review
2014
Review
2014
Nontuberculous mycobacterial infections in children with inborn errors of the immune system.
Highly Cited
2012
Highly Cited
2012
FIP3-endosome-dependent formation of the secondary ingression mediates ESCRT-III recruitment during cytokinesis
The final cytokinesis event involves severing of the connecting intercellular bridge (ICB) between daughter cells. FIP3-positive… 
Highly Cited
2008
Highly Cited
2008
Sequential Cyk‐4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis
Cytokinesis is a highly regulated and dynamic event that involves the reorganization of the cytoskeleton and membrane… 
Highly Cited
2007
Highly Cited
2007
Molecular characterization of Rab11-FIP3 binding to ARF GTPases.
Highly Cited
2007
Highly Cited
2007
Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.
The regulatory subunit NEMO is involved in the mechanism of activation of IkappaB kinase (IKK), the kinase complex that controls… 
Highly Cited
2006
Highly Cited
2006
Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.
Highly Cited
2005
Highly Cited
2005
A new mutation in exon 7 of NEMO gene: late skewed X-chromosome inactivation in an incontinentia pigmenti female patient with immunodeficiency
Incontinentia pigmenti is an X-linked genodermatosis, lethal in males. Affected females survive because of X-chromosome… 
Highly Cited
1999
Highly Cited
1999
Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis.
FIP-3 (14.7K interacting protein) was discovered during a search for cell proteins that could interact with an adenovirus protein… 
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