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IKBKE gene

Known as: IKKI, I-KAPPA-B KINASE-EPSILON, IKK-i 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Triple-negative breast cancers (TNBCs) are a heterogeneous set of cancers that are defined by the absence of hormone receptor… Expand
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Highly Cited
2014
Highly Cited
2014
UNLABELLED Recently, the rationale for combining targeted therapy with immunotherapy has come to light, but our understanding of… Expand
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Highly Cited
2011
Highly Cited
2011
Interleukin 17 (IL-17) is critical in the pathogenesis of inflammatory and autoimmune diseases. Here we report that Act1, the key… Expand
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Highly Cited
2011
Highly Cited
2011
Background: Activation of Akt has been shown to depend on PI3K, PDK1, and mTORC2 complex as well as PH domain of Akt. Results… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT The IκB kinase-related kinases, TBK1 and IKKi, were recently shown to be responsible for the C-terminal phosphorylation… Expand
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Highly Cited
2007
Highly Cited
2007
The karyotypic chaos exhibited by human epithelial cancers complicates efforts to identify mutations critical for malignant… Expand
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Highly Cited
2007
Highly Cited
2007
The expression of antiviral genes during infection is controlled by inducible transcription factors such as IRF3 (interferon… Expand
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Highly Cited
2006
Highly Cited
2006
The innate immune system recognizes nucleic acids during infection or tissue damage; however, the mechanisms of intracellular… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Antiviral innate immune responses can be triggered by accumulation of intracellular nucleic acids resulting from virus… Expand
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Highly Cited
2004
Highly Cited
2004
The effective interaction GXPF1 for shell-model calculations in the full $pf$ shell is tested in detail from various viewpoints… Expand
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