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NF-AT

Known as: NFAT-1, Nuclear Factor of Activated T-cells 
NFAT is a multi-subunit transcription complex that includes homo- or hetero-dimers of FOS and JUN proteins. NFATC, the Dorsal/Rel family cytosolic… 
National Institutes of Health

Related topics

Related topics

12 relations
Cell NucleusCytoplasmHomo sapiensNuclear Factor of Activated T-Cells, Cytoplasmic 1

Broader (1)

NFATC Transcription Factors

Papers overview

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2017
2017
Telmisartan suppresses cardiac hypertrophy by inhibiting cardiomyocyte apoptosis via the NFAT/ANP/BNP signaling pathway
Telmisartan, a type of angiotensin II (Ang II) receptor inhibitor, is a common agent used to treat hypertension in the clinic… 
Highly Cited
2016
Highly Cited
2016
Modulatory effects of thymol and carvacrol on inflammatory transcription factors in lipopolysaccharide-treated macrophages
Abstract Inflammation is a crucial factor in the pathogenesis of numerous diseases. This study sought to evaluate the effects of… 
Highly Cited
1998
Highly Cited
1998
Granulocyte-macrophage colony-stimulating factor gene transcription is directly repressed by the vitamin D3 receptor. Implications for allosteric influences on nuclear receptor structure and function…
The primary function of activated T lymphocytes is to produce various cytokines necessary to elicit an immune response; these… 
Highly Cited
1997
Highly Cited
1997
Intronic Enhancer Activity of the Eosinophil-derived Neurotoxin (RNS2) and Eosinophil Cationic Protein (RNS3) Genes Is Mediated by an NFAT-1 Consensus Binding Sequence*
The eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are both small, cationic ribonuclease toxins that… 
Highly Cited
1993
Highly Cited
1993
Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter.
We show here that the immediate upstream region (from position -12 to -270) of the murine interleukin 4 (Il-4) gene harbors a… 
1992
1992
Probing protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 by in vivo footprinting
We have analyzed protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 in a productively… 
1992
1992
Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1
The function of a putative NFAT-1 site in the human immunodeficiency virus type 1 enhancer has been analyzed. Activation by the T… 
Highly Cited
1990
Highly Cited
1990
Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional…
Nuclear factor of activated T-cells (NFAT-1) is a transcription factor which is considered to be an important regulator in early… 
Highly Cited
1990
Highly Cited
1990
Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1
The negative regulatory element of human immunodeficiency virus type 1 is a 260-nucleotide-long sequence that decreases the rate… 
1990
1990
Nuclear events after activation of CD4+8+ thymocytes.
Functionally mature T cells respond to stimulation via the Ag receptor by secretion of IL-2 and/or other lymphokines and by… 
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