NFATC Transcription Factors

Known as: Nuclear Factors of Activated T Cells, NFAT Proteins, Transcription Factor NF-AT 
A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
RATIONALE Both nuclear factors of activated T cells (NFAT) and nuclear factor-κB (NFκB) are Rel homology domain (RHD)-containing… (More)
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Highly Cited
2011
Highly Cited
2011
Nuclear factor of activated T cells (NFAT) proteins are Ca(2+)-regulated transcription factors that control gene expression in… (More)
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Highly Cited
2010
Highly Cited
2010
Engagement of T cells with antigen-presenting cells requires T-cell receptor (TCR) stimulation at the immune synapse. We… (More)
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2009
2009
799 Sonia Sharma and Anjana Rao are in the Department of Pathology, Harvard Medical School, Immune Disease Institute and the… (More)
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Highly Cited
2008
Highly Cited
2008
Nuclear factor of activated T cells (NFAT) was first described as an activation and differentiation transcription factor in… (More)
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Highly Cited
2003
Highly Cited
2003
Activation of transcription factors by receptor mediated signaling is an essential step for T lymphocyte effector function… (More)
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Highly Cited
2000
Highly Cited
2000
The critical function of NFAT proteins in maintaining lymphoid homeostasis was revealed in mice lacking both NFATp and NFAT4 (DKO… (More)
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Review
2000
Review
2000
The macrolactam natural product, FK506 (Tacrolimus), acts as a powerful and clinically useful immnosuppressant through disruption… (More)
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2000
2000
The African swine fever virus protein A238L inhibits activation of NFAT transcription factor by binding calcineurin and… (More)
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Highly Cited
1999
Highly Cited
1999
NFAT transcription factors are related to NF-kappaB/Rel proteins and form cooperative complexes with Fos and Jun on DNA. We have… (More)
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