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NEDD8 gene

Known as: Nedd-8, NEURAL PRECURSOR CELL EXPRESSED, DEVELOPMENTALLY DOWNREGULATED 8, Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 Gene 
This gene plays a role in protein post-translational modification.
National Institutes of Health

Related topics

Related topics

4 relations
MorphogenesisNEDD8 protein, humanPost-Translational Protein ProcessingUbiquitinated Protein Degradation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
NEDD8-conjugated Cullin4 positive regulates antimicrobial peptides expression in Eriocheir sinensis.
2017
2017
NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage
NEDDylation has been shown to participate in the DNA damage pathway, but the substrates of neural precursor cell expressed… 
2017
2017
Profiling of Signaling Proteins in Penumbra After Focal Photothrombotic Infarct in the Rat Brain Cortex
In ischemic stroke, cell damage propagates from infarct core to surrounding tissue. To reveal proteins involved in… 
2015
2015
A lysine-to-arginine mutation on NEDD8 markedly reduces the activity of cullin RING E3 ligase through the impairment of neddylation cascades.
2012
2012
Administration of nedd-8 activating enzyme inhibitor and hypomethylating agent
The present invention relates to a method of treating cancer in a patient deemed necessary by the treatment of cancer. The method… 
2009
2009
Using RNA Interference to Identify Specific Modifiers of a Temperature-Sensitive, Embryonic-Lethal Mutation in the Caenorhabditis elegans Ubiquitin-Like Nedd8 Protein Modification Pathway E1…
The essential Caenorhabditis elegans gene rfl-1 encodes one subunit of a heterodimeric E1-activating enzyme in the Nedd8… 
2006
2006
Evolutionally conserved intermediates between ubiquitin and NEDD8.
2006
2006
Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications.
Ubiquitin-like proteins modify target proteins, altering their activities or causing them to be slated for degradation. These… 
2002
2002
Interaction with Nedd8, a Ubiquitin-like Protein, Enhances the Transcriptional Activity of the Aryl Hydrocarbon Receptor*
The aryl hydrocarbon receptor (AhR) is a ligand-activated member of the basic helix-loop-helix period aryl hydrocarbon nuclear… 
1999
1999
The von Hippel-Lindau Tumor Suppressor Gene Product Promotes, but Is Not Essential for, NEDD8 Conjugation to Cullin-2*
We have previously shown that human cullin-2 (Cul-2) is covalently modified at Lys-689 by NEDD8 (Wada, H., Yeh, E. T. H., and… 
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