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NEDD8 protein, human

Known as: Ubiquitin-Like Protein Nedd8, NEDD-8, Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8 
NEDD8 (81 aa, ~9 kDa) is encoded by the human NEDD8 gene. This protein plays a role in the mediation of ubiquitination.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Neddylation, the covalent attachment of ubiquitin-like protein Nedd8, of the Cullin-RING E3 ligase family regulates their… Expand
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Highly Cited
2003
Highly Cited
2003
E1 enzymes initiate ubiquitin-like protein (ubl) transfer cascades by catalyzing adenylation of the ubl's C terminus. An E1's… Expand
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Highly Cited
2003
Highly Cited
2003
Post-translational modification by ubiquitin-like proteins (Ublps) is an essential cellular regulatory mechanism. The Ublp NEDD8… Expand
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Highly Cited
2002
Highly Cited
2002
The Nedd8 ubiquitin-like protein modification pathway regulates cell-cycle progression. Our analysis of Nedd8 requirements… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT Regulation of NF-κB occurs through phosphorylation-dependent ubiquitination of IκBα, which is degraded by the 26S… Expand
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Highly Cited
2000
Highly Cited
2000
The SCF-ROC1 ubiquitin-protein isopeptide ligase (E3) ubiquitin ligase complex targets the ubiquitination and subsequent… Expand
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Highly Cited
2000
Highly Cited
2000
A ubiquitin-like modifier, NEDD8, is covalently attached to cullin-family proteins, but its physiological role is poorly… Expand
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Highly Cited
2000
Highly Cited
2000
Temporal control of p27(Kip1) (p27) degradation imposes periodicity in its activity during cell cycle progression and its… Expand
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Highly Cited
1999
Highly Cited
1999
Recently we found that NEDD8, a ubiquitin-like protein, was linked covalently to human cullin-4A (abbreviated Cul-4A) by a new… Expand
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Highly Cited
1998
Highly Cited
1998
NEDD8 is a ubiquitin (Ub)-like protein. Here we report a novel ubiquitinylation-related pathway for modification by NEDD8. NEDD8… Expand
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