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NCR1 gene

Known as: NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1, NK-p46, LY94 
This gene is involved in the activation of natural killer cell-mediated cytotoxicity.
National Institutes of Health

Related topics

Related topics

9 relations
Cell-Mediated CytolysisLigand BindingNCR1 protein, humanNCR1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Direct antiviral agents upregulate natural killer cell potential activity in chronic hepatitis C patients
Direct antiviral agents (DAAs) can eliminate hepatitis C virus rapidly and make chronic hepatitis C (CHC) curable. The changes in… 
2016
2016
Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B…
Previous studies from Multhoff and colleagues reported that plasma membrane Hsp70 acts as a tumour-specific recognition structure… 
Highly Cited
2012
Highly Cited
2012
Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
HDACi are being used as a novel, therapeutic approach for leukemias and other hematological malignancies. However, their effect… 
2012
2012
Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in systemic autoimmune diseases
Objectives: A defined role for natural killer (NK) cells and their activating receptors in autoimmunity has not been clearly… 
2011
2011
Binding of natural cytotoxicity receptor NKp46 to sulfate- and α2,3-NeuAc-containing glycans and its mutagenesis.
Review
2009
Review
2009
Bovine natural killer cells.
2008
2008
Bovine WC1(-) gammadeltaT cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18.
2004
2004
Analysis of the natural killer mediated immune response in metastatic renal cell carcinoma patients
Metastatic renal cell carcinomas (MRCC) are considered as immunogeneic tumors on the basis of the clinical responses observed in… 
Highly Cited
2003
Highly Cited
2003
Crystal Structure of the Human Natural Killer (NK) Cell Activating Receptor NKp46 Reveals Structural Relationship to Other Leukocyte Receptor Complex Immunoreceptors*
Natural cytotoxicity receptors (NCR) mediate lysis of a variety of tumor and virus-infected cells by natural killer (NK) cells… 
1999
1999
Protein-bound polysaccharide (PSK) induces cytotoxic activity in the NKL human natural killer cell line
We studied the effect of protein-bound polysaccharide PSK on the activation of the human natural killer cell line NKL. We… 
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