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NC 6300

Known as: NC-6300, NC6300 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

EpirubicinProteins
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A Phase 1b Dose Escalation Trial of NC-6300 (Nanoparticle Epirubicin) in Patients with Advanced Solid Tumors or Advanced, Metastatic, or Unresectable Soft-tissue Sarcoma
Purpose: NC-6300 is a novel nanoparticle formulation of epirubicin that has a pH-sensitive linker conjugated to epirubicin. It… 
2020
2020
Reinforcement of antitumor effect of micelles containing anticancer drugs by binding of an anti-tissue factor antibody without direct cytocidal effects.
2019
2019
Function of Epirubicin-Conjugated Polymeric Micelles in Sonodynamic Therapy
The combinatory use of high-intensity focused ultrasound (HIFU) and epirubicin (EPI)-conjugated polymeric micellar nanoparticles… 
2017
2017
Sonodynamic Therapy Based on Combined Use of Low Dose Administration of Epirubicin-Incorporating Drug Delivery System and Focused Ultrasound.
2016
2016
Utility of epirubicin‐incorporating micelles tagged with anti‐tissue factor antibody clone with no anticoagulant effect
Tissue factor (TF), an initiator of the extrinsic blood coagulation cascade, is overexpressed in different types of cancer… 
Review
2016
Review
2016
Chapter 7:Anticancer Agent-Incorporating Polymeric Micelles: from Bench to Bedside
There are two main concepts in drug delivery systems (DDS): passive targeting and active targeting. The passive targeting system… 
2015
2015
Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models
For the creation of a successful antibody–drug conjugate (ADC), both scientific and clinical evidence has indicated that highly… 
2013
2013
Abstract 4525: Combined antitumor activity of the epirubicin-incorporating polymeric micelle NC-6300 and the DACHPt-incorporating polymeric micelle NC-4016 in mice bearing human gastric cancer…
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Background: Several anticancer agent (ACA… 
2012
2012
Abstract LB-11: Reduced cardiotoxicity and improved antitumor effect of the epirubicin-incorporating micelle NC-6300 in a hepatocellular carcinoma model
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Background: Epirubicin, an anthracycline antitumor… 
Highly Cited
2011
Highly Cited
2011
Improved anti‐tumor activity of stabilized anthracycline polymeric micelle formulation, NC‐6300
Anthracyclines have long been considered to be among the most active agents clinically available for the treatment of breast… 
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