Epirubicin

Known as: epi-ADR, Epirubicina, 4' Epi Adriamycin 
A 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby… (More)

Topic mentions per year

Topic mentions per year

1950-2017
010020019502016

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE Breast cancer stem cells have been shown to be associated with resistance to chemotherapy in vitro, but their clinical… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Docetaxel has not been compared with vinorelbine as adjuvant treatment of early breast cancer. Efficacy and long-term… (More)
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Highly Cited
2008
Highly Cited
2008
To the Editor: Cunningham et al. (Jan. 3 issue)1 state that capecitabine and oxaliplatin are equivalent to f luorouracil and… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE The PACS 01 trial compared six cycles of fluorouracil, epirubicin, and cyclophosphamide (FEC) with a sequential regimen… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The objective of this study was to determine whether the addition of trastuzumab to chemotherapy in the neoadjuvant… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The aim of the study was to evaluate the predictive value of HER2 and topoisomerase IIalpha gene (TOP2A) for the efficacy… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… (More)
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Highly Cited
1997
Highly Cited
1997
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and… (More)
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