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Epirubicin

Known as: epi-ADR, Epirubicina, 4' Epi Adriamycin 
A 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby… Expand
National Institutes of Health

Related topics

Related topics

48 relations
100 ML Epirubicin Hydrochloride 2 MG/ML Injection100 ML Epirubicin Hydrochloride 2 MG/ML Injection [Ellence]Drug AllergyIn Blood
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Narrower (30)

3'-deamino-3'-hydroxydoxorubicinCEFT protocolCEO-PE protocolCEOP-B protocol
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Broader (1)

Antibiotics, Antineoplastic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative…
PURPOSE This phase III study compared the efficacy and safety of bevacizumab (BV) when combined with several standard… Expand
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Highly Cited
2011
Highly Cited
2011
ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance
In this report, we investigated the role and regulation of forkhead box M1 (FOXM1) in breast cancer and epirubicin resistance. We… Expand
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Highly Cited
2011
Highly Cited
2011
Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development
Epirubicin (EPI) is one of the most effective drugs against cancer. But the acquired resistance of cancer cells to EPI is… Expand
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Highly Cited
2010
Highly Cited
2010
Laminar analysis of 7T BOLD using an imposed spatial activation pattern in human V1
With sufficient image encoding, high-resolution fMRI studies are limited by the biological point-spread of the hemodynamic signal… Expand
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Highly Cited
2010
Highly Cited
2010
An exploratory study of body composition as a determinant of epirubicin pharmacokinetics and toxicity
PurposeAlthough body composition has emerged as an important predictor of drug efficacy and toxicity, explanations for this… Expand
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Highly Cited
2001
Highly Cited
2001
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… Expand
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Highly Cited
2000
Highly Cited
2000
Promotive effect of brassinosteroids on cell division involves a distinct CycD3-induction pathway in Arabidopsis.
  • Yan Hu, Fang Bao, J Li
  • The Plant journal : for cell and molecular…
  • 2000
    • Corpus ID: 42662566
Brassinosteroids (BRs) are steroid hormones that play an essential role in plant growth and development. However, the… Expand
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Highly Cited
1998
Highly Cited
1998
Live-epikeratophakia for keratoconus.
PURPOSE To assess the clinical feasibility of refractive live-epikeratophakia (L-EPI) for early keratoconus to cap, rather than… Expand
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Review
1996
Review
1996
Epithelial M Cells: Gateways for Mucosal Infection and Immunization
M cell transport is an important factor in induction of mucosal immune responses and is exploited by pathogenic microorganisms… Expand
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Highly Cited
1995
Highly Cited
1995
Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer.
A phase III randomised study, comparing treatment with fluorouracil, epidoxorubicin and methotrexate (FEMTX) with the best… Expand
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