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Epirubicin
Known as:
epi-ADR
, Epirubicina
, 4' Epi Adriamycin
Â
(More)
A 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby…Â
(More)
Topic mentions per year
Topic mentions per year
1950-2017
0
100
200
1950
2016
Related topics
Related topics
38 relations
Narrower (17)
3'-deamino-3'-hydroxydoxorubicin
CEF regimen
CEP regimen
CEV protocol
(More)
Anthracyclines
Drug Allergy
Immunologic Adjuvants [MoA]
In Blood
(More)
Broader (2)
Antibiotics, Antineoplastic
Topoisomerase II Inhibitors
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Epirubicin
Mammary Neoplasms
Drug Allergy
agonists
Pregnancy
Neutropenia
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.
Tomonori Tanei
,
K. Morimoto
,
+5 authors
Shinzaburo Noguchi
Clinical cancer research : an official journal of…
2009
PURPOSE Breast cancer stem cells have been shown to be associated with resistance to chemotherapy in vitro, but their clinical…Â
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Is this relevant?
Highly Cited
2009
Highly Cited
2009
Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer Trial.
Heikki Olavi Joensuu
,
Petri Bono
,
+17 authors
Pirkko-Liisa Kellokumpu-Lehtinen
Journal of clinical oncology : official journal…
2009
PURPOSE Docetaxel has not been compared with vinorelbine as adjuvant treatment of early breast cancer. Efficacy and long-term…Â
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Is this relevant?
Highly Cited
2008
Highly Cited
2008
Capecitabine and oxaliplatin for advanced esophagogastric cancer.
Edwin Boelke
,
Matthias Peiper
,
Wilfried Budach
The New England journal of medicine
2008
To the Editor: Cunningham et al. (Jan. 3 issue)1 state that capecitabine and oxaliplatin are equivalent to f luorouracil and…Â
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Highly Cited
2006
Highly Cited
2006
Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.
David C. Cunningham
,
William H. Allum
,
+13 authors
MAGIC Trial Participants
The New England journal of medicine
2006
BACKGROUND A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable…Â
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Highly Cited
2006
Highly Cited
2006
Sequential adjuvant epirubicin-based and docetaxel chemotherapy for node-positive breast cancer patients: the FNCLCC PACS 01 Trial.
Henri Roché
,
Pierre Fumoleau
,
+17 authors
Bernard Asselain
Journal of clinical oncology : official journal…
2006
PURPOSE The PACS 01 trial compared six cycles of fluorouracil, epirubicin, and cyclophosphamide (FEC) with a sequential regimen…Â
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Highly Cited
2005
Highly Cited
2005
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth…
Aman U. Buzdar
,
Nuhad K. Ibrahim
,
+17 authors
Gabriel N Hortobagyi
Journal of clinical oncology : official journal…
2005
PURPOSE The objective of this study was to determine whether the addition of trastuzumab to chemotherapy in the neoadjuvant…Â
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Highly Cited
2005
Highly Cited
2005
retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil…
Ann Søegaard Knoop
,
H. Lottrup Knudsen
,
+8 authors
Bent Ejlertsen
Journal of clinical oncology : official journal…
2005
PURPOSE The aim of the study was to evaluate the predictive value of HER2 and topoisomerase IIalpha gene (TOP2A) for the efficacy…Â
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Highly Cited
2002
Highly Cited
2002
Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) With epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer.
P Ross
,
Marianne Nicolson
,
+9 authors
Aaron D. Norman
Journal of clinical oncology : official journal…
2002
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and…Â
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Is this relevant?
Highly Cited
2001
Highly Cited
2001
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
Dennis J. Slamon
,
Brian R. Leyland-Jones
,
+9 authors
L. Norton
The New England journal of medicine
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30…Â
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Highly Cited
1997
Highly Cited
1997
Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer.
Alan Webb
,
D. Cunningham
,
+16 authors
M. Meehan
Journal of clinical oncology : official journal…
1997
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and…Â
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Is this relevant?