FAQ

Epirubicin

Known as: epi-ADR, Epirubicina, 4' Epi Adriamycin 
A 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby… (More)

Topic mentions per year

Topic mentions per year

1950-2017
010020019502016

Related topics

Related topics

38 relations

Narrower (17)

3'-deamino-3'-hydroxydoxorubicinCEF regimenCEP regimenCEV protocol
(More)
AnthracyclinesDrug AllergyImmunologic Adjuvants [MoA]In Blood
(More)

Broader (2)

Antibiotics, AntineoplasticTopoisomerase II Inhibitors

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Epirubicin
Mammary Neoplasms
Drug Allergy
agonists
Pregnancy
Neutropenia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.
PURPOSE Breast cancer stem cells have been shown to be associated with resistance to chemotherapy in vitro, but their clinical… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer Trial.
PURPOSE Docetaxel has not been compared with vinorelbine as adjuvant treatment of early breast cancer. Efficacy and long-term… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Capecitabine and oxaliplatin for advanced esophagogastric cancer.
To the Editor: Cunningham et al. (Jan. 3 issue)1 state that capecitabine and oxaliplatin are equivalent to f luorouracil and… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.
BACKGROUND A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Sequential adjuvant epirubicin-based and docetaxel chemotherapy for node-positive breast cancer patients: the FNCLCC PACS 01 Trial.
PURPOSE The PACS 01 trial compared six cycles of fluorouracil, epirubicin, and cyclophosphamide (FEC) with a sequential regimen… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth…
PURPOSE The objective of this study was to determine whether the addition of trastuzumab to chemotherapy in the neoadjuvant… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil…
PURPOSE The aim of the study was to evaluate the predictive value of HER2 and topoisomerase IIalpha gene (TOP2A) for the efficacy… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) With epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer.
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… (More)
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer.
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and… (More)
Is this relevant?