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NAT2 wt Allele

Known as: NAT-2, NAT2*4 Allele, N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) wt Allele 
Human NAT2 wild-type allele is located in the vicinity of 8p22 and is approximately 10 kb in length. This allele, which encodes arylamine N… 
National Institutes of Health

Related topics

Related topics

6 relations
AcetylationHomo sapiensLupus Erythematosus, SystemicMetabolic Detoxication, Drug

Broader (1)

NAT2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Correction for The Cardiolipin Transacylase, Tafazzin, Associates with Two Distinct Respiratory Components Providing Insight into Barth Syndrome
Mutations in the mitochondrial cardiolipin (CL) transacylase, tafazzin (Taz1p), result in the X-linked cardioskeletal myopathy… 
2006
2006
Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation.
Highly Cited
2004
Highly Cited
2004
Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability.
Autosomal dominant and recessive forms of progressive external ophthalmoplegia (adPEO and arPEO) are mitochondrial disorders… 
Highly Cited
2002
Highly Cited
2002
Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids.
The expression of mitochondrial and hydrogenosomal ADP/ATP carriers (AACs) from plants, rat and the anaerobic chytridiomycete… 
Highly Cited
1997
Highly Cited
1997
Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours.
Arylamine N-acetyltransferases (NATs) are encoded at two loci on 8p22, a region subject to deletions in bladder tumours. The two… 
Highly Cited
1996
Highly Cited
1996
Probing the role of positive residues in the ADP/ATP carrier from yeast. The effect of six arginine mutations of oxidative phosphorylation and AAC expression.
ADP/ATP transport is the terminal step of oxidative phosphorylation in mitochondria. In this paper seven mutants of AAC2 from… 
Highly Cited
1994
Highly Cited
1994
Metabolic activation and carcinogen-DNA adduct detection in human larynx.
Putative carcinogen-DNA adducts in human larynx tissues (n = 25) from smoker and non/ex-smoker patients were examined by 32P… 
Highly Cited
1990
Highly Cited
1990
A third ADP/ATP translocator gene in yeast.
Highly Cited
1990
Highly Cited
1990
Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria.
Highly Cited
1988
Highly Cited
1988
Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.
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