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NAT2 wt Allele

Known as: NAT-2, NAT2*4 Allele, N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) wt Allele 
Human NAT2 wild-type allele is located in the vicinity of 8p22 and is approximately 10 kb in length. This allele, which encodes arylamine N… 
National Institutes of Health

Related topics

Related topics

6 relations
AcetylationHomo sapiensLupus Erythematosus, SystemicMetabolic Detoxication, Drug

Broader (1)

NAT2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In vivo Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells
We had previously demonstrated the anti-diabetic potential and pancreatic protection of two thiazolidin-4-one derivatives… 
2006
2006
Influence of polymorphisms in xenobiotic‐metabolizing genes and DNA‐repair genes on diepoxybutane‐induced SCE frequency
Analysis of the combined effects of polymorphisms in genes encoding xenobiotic metabolizing enzymes (XMEs) and DNA repair… 
2006
2006
The structure of the second cytosolic loop of the yeast mitochondrial ADP/ATP carrier AAC2 is dependent on the conformational state.
Highly Cited
2004
Highly Cited
2004
Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability.
Autosomal dominant and recessive forms of progressive external ophthalmoplegia (adPEO and arPEO) are mitochondrial disorders… 
2002
2002
Induction of an unregulated channel by mutations in adenine nucleotide translocase suggests an explanation for human ophthalmoplegia.
Adenine nucleotide translocase (Ant) is primarily involved in ATP/ADP exchange across the mitochondrial inner membrane. Recently… 
Highly Cited
1997
Highly Cited
1997
Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours.
Arylamine N-acetyltransferases (NATs) are encoded at two loci on 8p22, a region subject to deletions in bladder tumours. The two… 
1994
1994
Molecular analysis of the arylamine N‐acetyltransferase polymorphism in a Spanish population
The arylamine N‐acetyltransferase (NAT‐2) polymorphism causes impaired drug metabolism in about half of the white population. By… 
1994
1994
The locus controlling pineal serotonin N-acetyltransferase activity (Nat-2) is located on mouse chromosome 11.
1993
1993
Function-based mapping of the yeast mitochondrial ADP/ATP translocator by selection for second site revertants.
Structure-function relationships in the yeast adenine nucleotide carrier (AAC2) were probed by genetic selection techniques in… 
Highly Cited
1990
Highly Cited
1990
Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria.
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