NAE1 gene

Known as: NEDD8 activating enzyme E1 subunit 1, AMYLOID BETA PRECURSOR PROTEIN-BINDING PROTEIN 1, ula-1 
This gene plays a role in the modulation of protein neddylation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
012320002018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Imatinib revolutionized the treatment of chronic myeloid leukemia (CML), but drug resistance and disease recurrence remain a… (More)
Is this relevant?
2017
2017
PURPOSE Liver metastasis is the major and direct cause of death in patients with uveal melanoma (UM). There is no effective… (More)
Is this relevant?
2017
2017
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA with a 5-year survival rate less… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2015
2015
Transmembrane receptors, such as the EGFR, are regulated by their turnover, which is dependent on the ubiquitin-proteasome system… (More)
  • table 1
  • table 2
  • table 3
  • figure 2
  • figure 2
Is this relevant?
2014
2014
Therapeutic intervention in neddylation pathway is an emerging area for cancer treatment. Herein, we evaluated the clinical… (More)
Is this relevant?
2014
2014
Neddylation, the covalent attachment of ubiquitin-like protein Nedd8, of the Cullin-RING E3 ligase family regulates their… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
2012
2012
The multiunit Cullin (CUL)-RING E3 ligase (CRL) controls diverse biological processes by targeting a mass of substrates for… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Therapies that target estrogen signaling have made a very considerable contribution to reducing mortality from breast cancer… (More)
Is this relevant?
2011
2011
The conjugation of the ubiquitin-like modifier NEURAL PRECURSOR CELL-EXPRESSED DEVELOPMENTALLY DOWN-REGULATED PROTEIN8/RELATED TO… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2000
2000
This work has identified the enzymes involved in the activation and conjugation of the ubiquitin-like protein NED-8 in… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?