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NAE1 gene

Known as: NEDD8 activating enzyme E1 subunit 1, AMYLOID BETA PRECURSOR PROTEIN-BINDING PROTEIN 1, ula-1 
This gene plays a role in the modulation of protein neddylation.
National Institutes of Health

Papers overview

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2016
2016
Neddylation is a post-translational protein modification process associated with carcinogenesis and cancer development. MLN4924… Expand
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Highly Cited
2014
Highly Cited
2014
Neddylation, the covalent attachment of ubiquitin-like protein Nedd8, of the Cullin-RING E3 ligase family regulates their… Expand
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2014
2014
Therapeutic intervention in neddylation pathway is an emerging area for cancer treatment. Herein, we evaluated the clinical… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND A number of oncoproteins and tumor suppressors are known to be neddylated, but whether the neddylation pathway is… Expand
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2013
2013
BackgroundHIV and SIV defeat antiviral proteins by usurping Cullin-RING E3 ubiquitin ligases (CRLs) and likely influence other… Expand
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2012
2012
The multiunit Cullin (CUL)-RING E3 ligase (CRL) controls diverse biological processes by targeting a mass of substrates for… Expand
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Highly Cited
2011
Highly Cited
2011
Therapies that target estrogen signaling have made a very considerable contribution to reducing mortality from breast cancer… Expand
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2005
2005
Rashes following immunization with the vaccine strain (vOka) of varicella-zoster virus (VZV) may occur in up to 5% of children… Expand
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2001
2001
Abstract. In the E1 state of the Na,K-ATPase all cations present in the cytoplasm compete for the ion binding sites. The mutual… Expand
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1995
1995
A dual-wavelength fluorimeter was constructed, which used two light emitting diodes (LEDs) to excite the fluorescence dye RH 421… Expand
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