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The DELLA Domain of GA INSENSITIVE Mediates the Interaction with the GA INSENSITIVE DWARF1A Gibberellin Receptor of Arabidopsis[W]
TLDR
The genetic interaction studies indicate that GAI and its close homolog REPRESSOR of ga1-3 are the major growth repressors in a GA receptor mutant background and it is proposed that the DELLA domain functions as a receiver domain for activated GA receptors. Expand
Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response
TLDR
It is shown that plants with reduced COP9 signalosome levels had decreased auxin response similar to loss-of-function mutants of the E3 ubiquitin ligase SCFTIR1, and that the COP9 signosome was required for efficient degradation of PSIAA6, a candidate substrate of SC FTIR1. Expand
The GATA-type transcription factors GNC and GNL/CGA1 repress gibberellin signaling downstream from DELLA proteins and PHYTOCHROME-INTERACTING FACTORS.
TLDR
It is established that GNC and GNL are functionally redundant regulators of germination, greening, elongation growth and flowering time and that both genes are potentially direct transcription targets of PIF transcription factors, and that their expression is up-regulated in pif mutant backgrounds. Expand
Gibberellin Regulates PIN-FORMED Abundance and Is Required for Auxin Transport–Dependent Growth and Development in Arabidopsis thaliana[C][W]
TLDR
It is shown that auxin transport is reduced in the inflorescences of Arabidopsis thaliana mutants deficient in GA biosynthesis and signaling, and that PIN protein levels recover to wild-type levels following GA treatment. Expand
COP9 signalosome revisited: a novel mediator of protein degradation.
TLDR
Although its precise role in the process of protein degradation remains to be established, the COP9 signalosome is a positive regulator of E3 ubiquitin ligases that functions at least in part by mediating the deconjugation of the NEDD8/RUB-modification from the cullin subunit of SCF-type E3 complexes. Expand
The COP9 signalosome (CSN): an evolutionary conserved proteolysis regulator in eukaryotic development.
TLDR
A summary of the role of CSN in regulating protein degradation and in eukaryotic development is provided and CSN may also regulate proteolysis by its association with protein kinases and deubiquitylating enzymes. Expand
The Deubiquitinating Enzyme AMSH3 Is Required for Intracellular Trafficking and Vacuole Biogenesis in Arabidopsis thaliana[C][W]
TLDR
Evidence is presented for a role of deubiquitination in intracellular trafficking and vacuole biogenesis and for the role of AMSH3 in the development of cellular organelles. Expand
Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID
TLDR
It is shown that PIN-mediated auxin transport is directly activated by D6 PROTEIN KINASE (D6PK) and PINOID (PID)/WAG kinases of the Arabidopsis AGCVIII kinase family and that D6PKs and PID have differential phosphosite preferences. Expand
The Deubiquitinating Enzyme AMSH1 and the ESCRT-III Subunit VPS2.1 Are Required for Autophagic Degradation in Arabidopsis[C][W][OPEN]
TLDR
This study shows that AMSH1, an AMSH3-related deubiquitinating enzyme, interacts with the endocytosis machinery through the ESCRT-III subunit VPS2.1 and that impairment of both AMSH 1 and VPS 2.1 causes early senescence and hypersensitivity to artificial carbon starvation in the dark similar to previously reported autophagy mutants. Expand
Cross-Repressive Interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the Control of Greening, Cold Tolerance, and Flowering Time in Arabidopsis1[W][OPEN]
TLDR
The case of a cross-repressive interaction between the GATA factors GNC and GNL and the MADS box transcription factor SOC1 in flowering time control on the one side and greening and cold tolerance on the other that may be governed by the various signaling inputs that are integrated at the level of SOC1 expression is supported. Expand
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