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NADPH dehydrogenase activity

Known as: NAD(P)H2 dehydrogenase (quinone), NADPH-dehydrogenase activity, NADPH2-dehydrogenase activity 
Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. [EC:1.14.13.39]
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Oxidative stress and inflammation interact in the development of diabetic atherosclerosis. Intracellular hyperglycemia promotes… Expand
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Review
2018
Review
2018
The NFE2L2 gene encodes the transcription factor Nrf2 best known for regulating the expression of antioxidant and detoxification… Expand
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Highly Cited
2001
Highly Cited
2001
Endothelial nitric oxide synthase (eNOS) is activated by phosphorylation of serine 1177 by the protein kinase Akt/PKB. Since… Expand
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Review
2001
Review
2001
Cardiovascular risk factors cluster in obese individuals. Insulin resistance emerges as a common pathogenetic denominator… Expand
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Highly Cited
2000
Highly Cited
2000
  • ohn, R. D., +7 authors RNOLD
  • 2000
  • Corpus ID: 20311470
F RANK M. S ACKS , M.D., M ARC A. P FEFFER , M.D., P H .D., L EMUEL A. M OYE , M.D., P H .D., J EAN L. R OULEAU , M.D., J OHN D… Expand
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Highly Cited
2000
Highly Cited
2000
Huntington disease is an autosomal dominant neurodegenerative disease with no effective treatment. Minocycline is a tetracycline… Expand
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Highly Cited
1991
Highly Cited
1991
NADPH diaphorase staining neurons, uniquely resistant to toxic insults and neurodegenerative disorders, have been colocalized… Expand
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Highly Cited
1991
Highly Cited
1991
NADPH diaphorase histochemistry selectively labels a number of discrete populations of neurons throughout the nervous system… Expand
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Highly Cited
1991
Highly Cited
1991
Nitric oxide is a free radical that has been recently recognized as a neural messenger molecule. Nitric oxide synthase has now… Expand
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Highly Cited
1990
Highly Cited
1990
  • D. Bredt, S. Snyder
  • Proceedings of the National Academy of Sciences…
  • 1990
  • Corpus ID: 27668003
Nitric oxide mediates vascular relaxing effects of endothelial cells, cytotoxic actions of macrophages and neutrophils, and… Expand
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