NADPH dehydrogenase activity

Known as: NAD(P)H2 dehydrogenase (quinone), NADPH-dehydrogenase activity, NADPH2-dehydrogenase activity 
Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. [EC:1.14.13.39]
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Changes in plasma nitrite concentration in the human forearm circulation have recently been shown to reflect acute changes in… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although abnormal L-arginine NO signaling contributes to endothelial dysfunction in the aging cardiovascular system… (More)
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Highly Cited
2001
Highly Cited
2001
Endothelial nitric oxide synthase (eNOS) is activated by phosphorylation of serine 1177 by the protein kinase Akt/PKB. Since… (More)
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Highly Cited
2001
Highly Cited
2001
The activity of the endothelial nitric oxide synthase (eNOS) can be regulated independently of an increase in Ca(2+) by the… (More)
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Highly Cited
2001
Highly Cited
2001
The plasma level of NO(x), i.e., the sum of NO(2)- and NO(3)-, is frequently used to assess NO bioavailability in vivo. However… (More)
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Highly Cited
2000
Highly Cited
2000
Huntington disease is an autosomal dominant neurodegenerative disease with no effective treatment. Minocycline is a tetracycline… (More)
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Highly Cited
1991
Highly Cited
1991
NADPH diaphorase histochemistry selectively labels a number of discrete populations of neurons throughout the nervous system… (More)
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Highly Cited
1991
Highly Cited
1991
NADPH diaphorase staining neurons, uniquely resistant to toxic insults and neurodegenerative disorders, have been colocalized… (More)
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Highly Cited
1991
Highly Cited
1991
Nitric oxide is a free radical that has been recently recognized as a neural messenger molecule. Nitric oxide synthase has now… (More)
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Highly Cited
1990
Highly Cited
1990
Nitric oxide mediates vascular relaxing effects of endothelial cells, cytotoxic actions of macrophages and neutrophils, and… (More)
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