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Management of orbital subperiosteal abscess in children.
Assessment of the efficacy and safety of transnasal endoscopic drainage of an orbital subperiosteal abscess in children and of the route of surgical drainage found that the external approach was associated with a longer hospital stay than either the endoscopic or the intravenous antibiotic approach. Expand
Endoscopic sinus surgery in cystic fibrosis: do patients benefit from surgery?
Although the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis patients through the objective parameters of steroid use, pulmonary function tests, and inpatient hospital days were examined, there was no statistically significant change in PFTs, or steroid requirements following ESS. Expand
Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance.
The lack of cross-resistance among cell lines selected for resistance to different alkylating agents, all of which have elevated GST-pi levels, indicates that increased levels of GST-PI cannot be the predominate mechanism for resistanceto the tested drugs in these cell lines. Expand
Drug-induced sleep endoscopy in persistent pediatric sleep-disordered breathing after adenotonsillectomy.
Findings from DISE suggest that multiple factors contribute to airway obstruction in persistent SDB after T&A, and further research can address the extent to which directed surgical treatment can improve outcomes in these patients. Expand
Propranolol in the management of airway infantile hemangiomas.
In the first patient, propranolol was used when other treatments were ineffective or associated with intolerable adverse effects, and in the second and third patients, it was part of a dual regimen that resulted in rapid resolution of airway symptoms and allowed for quicker weaning of corticosteroids. Expand
Immunohistochemical characterization of nitric oxide synthase activity in squamous cell carcinoma of the head and neck.
The findings suggest that inducible nitric oxide synthase activity is present in squamous cell carcinomas of the head and neck, leading to the conclusion that inducers may play a significant role in tumor growth. Expand
Human beta-defensins 2 and -3 cointernalize with human immunodeficiency virus via heparan sulfate proteoglycans and reduce infectivity of intracellular virions in tonsil epithelial cells.
It is found that heparan sulfate proteoglycans on the apical surfaces of epithelial cells facilitate simultaneous binding of hBDs and HIV gp120 to the cell surface, which advances the understanding of the mechanisms of anti-HIV resistance in adult oral epithelium. Expand
Airway hemangiomas in PHACE syndrome
To describe the clinical presentation and airway characteristics of infants with airway hemangiomas and concomitant PHACE syndrome and to determine the prevalence of airway hemangiomas in PHACEExpand
Submucosal gland dysfunction as a primary defect in cystic fibrosis
Therapies directed at normalizing gland fluid secretion early in CF may thus reduce lung disease and suggest that defective airway submucosal gland function is an early, primary defect in CF. Expand