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N-type calcium channels

Known as: N Type VDCC, Calcium Channels, N Type, N-Type Calcium Channel 
CALCIUM CHANNELS that are concentrated in neural tissue. Omega toxins inhibit the actions of these channels by altering their voltage dependence.
National Institutes of Health

Related topics

Related topics

8 relations

Narrower (2)

Cacna1b protein, ratvoltage-dependent calcium channel (P-Q type)
In BloodProcess of secretionaspects of radiation effectschemical synthesis

Papers overview

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Highly Cited
2008
Highly Cited
2008
Local Ca2+ Influx through Ca2+ Release-activated Ca2+ (CRAC) Channels Stimulates Production of an Intracellular Messenger and an Intercellular Pro-inflammatory Signal*
Ca2+ entry through store-operated Ca2+ channels drives the production of the pro-inflammatory molecule leukotriene C4 (LTC4) from… 
Highly Cited
2006
Highly Cited
2006
Ca2+ influx through CRAC channels activates cytosolic phospholipase A2, leukotriene C4 secretion, and expression of c‐fos through ERK‐dependent and independent pathways in mast cells
Cytosolic phospholipase A2 (cPLA2) is a Ca2+‐dependent enzyme that mediates agonist‐dependent arachidonic acid release in most… 
Highly Cited
2004
Highly Cited
2004
Long-Chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes
Aims/hypothesisThe ATP-regulated potassium (KATP) channel in the pancreatic beta cell couples the metabolic state to electrical… 
Highly Cited
2000
Highly Cited
2000
G Protein Modulation of N-type Calcium Channels Is Facilitated by Physical Interactions between Syntaxin 1A and Gβγ*
The direct modulation of N-type calcium channels by G protein βγ subunits is considered a key factor in the regulation of… 
Highly Cited
2000
Highly Cited
2000
Syntaxin Modulation of Slow Inactivation of N-Type Calcium Channels
Syntaxin, a membrane protein vital in triggering vesicle fusion, interacts with voltage-gated N- and P/Q-type Ca2+channels. This… 
Highly Cited
1999
Highly Cited
1999
Metabotropic GABA receptors facilitate L‐type and inhibit N‐type calcium channels in single salamander retinal neurons
1 Whole‐cell voltage clamp experiments were performed on isolated spiking retinal neurons from the salamander retina. Calcium… 
Highly Cited
1993
Highly Cited
1993
Altered prevalence of gating modes in neurotransmitter inhibition of N-type calcium channels
G protein-mediated inhibition of voltage-activated calcium channels by neurotransmitters has important consequences for the… 
Review
1982
Review
1982
Ionic channels in skeletal muscle.
There is now considerable evidence that ions can move across the cell membrane through voltage-gated aqueous pores called "ionic… 
Highly Cited
1981
Highly Cited
1981
Ionic channels involved in the LHRH and SRIF release from rat mediobasal hypothalamus.
A superfusion system was used in order to investigate the ionic requirements of luteinizing hormone releasing hormone (LHRH) and… 
Review
1980
Review
1980
Calcium ionic channels in electrically excitable membrane
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