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- Publications
- Influence
Specificity and regulation of a synaptic vesicle docking complex
- J. Pevsner, Shu-Chan Hsu, J. Braun, N. Calakos, R. Scheller
- Chemistry, Medicine
- Neuron
- 1 August 1994
Synaptic vesicles are proposed to dock at the presynaptic plasma membrane through the interaction of two integral membrane proteins of synaptic vesicles, VAMP and synaptotagmin, and two plasma… Expand
The Cysteine String Secretory Vesicle Protein Activates Hsc70 ATPase*
- J. Braun, S. M. Wilbanks, R. Scheller
- Biology, Medicine
- The Journal of Biological Chemistry
- 18 October 1996
Cysteine string protein (CSP) is a 34 kDa secretory vesicle protein bearing a “J-domain” as well as a palmitoylated cysteine-rich “string” region used for membrane attachment. Mutation of the CSP… Expand
Regulation of the synthesis, processing and translocation of lipoprotein lipase.
- J. Braun, D. Severson
- Biology, Medicine
- The Biochemical journal
- 15 October 1992
Cysteine string protein (CSP) is an insulin secretory granule‐associated protein regulating β‐cell exocytosis
- H. Brown, O. Larsson, +14 authors B. Meister
- Biology, Medicine
- The EMBO journal
- 1 September 1998
Cysteine string proteins (CSPs) are novel synaptic vesicle‐associated protein components characterized by an N‐terminal J‐domain and a central palmitoylated string of cysteine residues. The cellular… Expand
G Protein Modulation of N-type Calcium Channels Is Facilitated by Physical Interactions between Syntaxin 1A and Gβγ*
- S. E. Jarvis, J. M. Magga, A. Beedle, J. Braun, G. Zamponi
- Biology, Medicine
- The Journal of Biological Chemistry
- 3 March 2000
The direct modulation of N-type calcium channels by G protein βγ subunits is considered a key factor in the regulation of neurotransmission. Some of the molecular determinants that govern the binding… Expand
Crosstalk between huntingtin and syntaxin 1A regulates N-type calcium channels
- L. A. Swayne, Lina Chen, S. Hameed, W. Barr, J. Braun
- Biology, Medicine
- Molecular and Cellular Neuroscience
- 1 November 2005
We have identified a novel interaction between huntingtin (htt) and N-type calcium channels, a channel key in coupling calcium influx with synaptic vesicle exocytosis. Htt is a widely expressed… Expand
The cysteine string protein multimeric complex.
- L. A. Swayne, K. Beck, J. Braun
- Biology, Medicine
- Biochemical and biophysical research…
- 15 September 2006
Cysteine string protein (CSPalpha) is a member of the cellular folding machinery that is located on regulated secretory vesicles. We have previously shown that CSPalpha in association with Hsc70… Expand
Cysteine String Protein (CSP) Inhibition of N-type Calcium Channels Is Blocked by Mutant Huntingtin*
- Linda C. Miller, L. A. Swayne, +5 authors J. Braun
- Biology, Medicine
- Journal of Biological Chemistry
- 26 December 2003
Cysteine string protein (CSP), a 34-kDa molecular chaperone, is expressed on synaptic vesicles in neurons and on secretory vesicles in endocrine, neuroendocrine, and exocrine cells. CSP can be found… Expand
Syntaxin 1A Co‐Associates with Native Rat Brain and Cloned Large Conductance, Calcium‐Activated Potassium Channels in situ
Large conductance, calcium‐activated potassium channels (BKCa channels) are regulated by several distinct mechanisms, including phosphorylation/dephosphorylation events and protein‐protein… Expand
Characterization of the G alpha(s) regulator cysteine string protein.
- M. Natochin, T. Campbell, +4 authors J. Braun
- Medicine
- The Journal of biological chemistry
- 2005
Cysteine string protein (CSP) is an abundant regulated secretory vesicle protein that is composed of a string of cysteine residues, a linker domain, and an N-terminal J domain characteristic of the… Expand