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N-ras Genes

Known as: Oncogene N-RAS, N ras Oncogenes, Neuroblastoma RAS Viral Oncogene Homolog 
Human Oncogene N-RAS is a mutated variant of NRAS Gene (RAS Family), which encodes p21 N-Ras Protein, a monomeric GTPase involved in transmembrane… 
National Institutes of Health

Related topics

Related topics

9 relations
1p13Colorectal CarcinomaHomo sapiensNRAS gene

Broader (1)

Genes, ras

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment
Juvenile myelomonocytic leukemia (JMML) is an aggressive leukemia of early childhood characterized by aberrant proliferation of… 
2014
2014
Mutational status of KRAS, NRAS, and BRAF in primary clear cell ovarian carcinoma
Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer with characteristic biological features and… 
2014
2014
Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT
There is conflicting evidence on the predictive role of KRAS status when cetuximab is added to oxaliplatin-based regimens. This… 
2012
2012
NRAS Mutations in Noonan Syndrome
Noonan syndrome is a genetically heterogeneous disorder caused by mutations in PTPN11, SOS1, RAF1 and less frequently in KRAS… 
Review
2011
Review
2011
New Strategies in Metastatic Melanoma: Oncogene-Defined Taxonomy Leads to Therapeutic Advances
The discovery of BRAF and KIT mutations provided the first basis for a molecular classification of cutaneous melanoma on… 
Highly Cited
2010
Highly Cited
2010
Tumor and Stem Cell Biology Cancer Research A Mouse Model of Melanoma Driven by Oncogenic KRAS
Authors' Pathology Institute of Note: Sup Research O Correspon Institute of ed Kingdo marais@icr 
2009
2009
Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma
Amplification of the 11q13 chromosomal region is a common event in primary melanomas. Several candidate genes are localized at… 
Highly Cited
2007
Highly Cited
2007
Oncogenic NRAS, KRAS, and HRAS exhibit different leukemogenic potentials in mice.
RAS proteins are small GTPases that play a central role in transducing signals that regulate cell proliferation, survival, and… 
2005
2005
Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells.
Mutations in the three closely related RAS genes, HRAS, KRAS, and NRAS are among the most common mutations found in human cancer… 
1990
1990
Detection of preferential NRAS mutations in human male germ cell tumors by the polymerase chain reaction
We have studied 31 male germ cell tumors (GCTs) for probable mutations in codons 12, 13, and 61 of HRAS, KRAS, and NRAS oncogenes… 
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