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N-ras Genes

Known as: Oncogene N-RAS, N ras Oncogenes, Neuroblastoma RAS Viral Oncogene Homolog 
Human Oncogene N-RAS is a mutated variant of NRAS Gene (RAS Family), which encodes p21 N-Ras Protein, a monomeric GTPase involved in transmembrane… 
National Institutes of Health

Related topics

Related topics

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1p13Colorectal CarcinomaHomo sapiensNRAS gene

Broader (1)

Genes, ras

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma
HRAS, KRAS, and NRAS, highly homologous proteins, are often mutationally activated in cancer. Usually, mutations cluster in… 
2014
2014
Mutational status of KRAS, NRAS, and BRAF in primary clear cell ovarian carcinoma
Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer with characteristic biological features and… 
2014
2014
Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT
There is conflicting evidence on the predictive role of KRAS status when cetuximab is added to oxaliplatin-based regimens. This… 
2012
2012
NRAS Mutations in Noonan Syndrome
Noonan syndrome is a genetically heterogeneous disorder caused by mutations in PTPN11, SOS1, RAF1 and less frequently in KRAS… 
2012
2012
Constitutional NRAS mutations are rare among patients with Noonan syndrome or juvenile myelomonocytic leukemia
Recently, germline mutations of NRAS have been shown to be associated with Noonan syndrome (NS), a relatively common… 
2012
2012
Clinicopathologic Features of V600E and V600K Melanoma—Letter
The presence of a BRAF mutation in a melanoma tumor predicts response to BRAF inhibitors; however, the biological characteristics… 
2010
2010
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.
The t(10;11) translocation results in a CALM-AF10 fusion gene in a subset of leukemia patients. Expression of a CALM-AF10… 
2009
2009
Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma
Amplification of the 11q13 chromosomal region is a common event in primary melanomas. Several candidate genes are localized at… 
Highly Cited
1992
Highly Cited
1992
Detection of RAS mutations in archival testicular germ cell tumors by polymerase chain reaction and oligonucleotide hybridization
Preliminary studies of RAS mutational activation in human testicular germ cell neoplasms have yielded conflicting results… 
1990
1990
Detection of preferential NRAS mutations in human male germ cell tumors by the polymerase chain reaction
We have studied 31 male germ cell tumors (GCTs) for probable mutations in codons 12, 13, and 61 of HRAS, KRAS, and NRAS oncogenes… 
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