N-ras Genes

Known as: Oncogene N-RAS, N ras Oncogenes, Neuroblastoma RAS Viral Oncogene Homolog 
Human Oncogene N-RAS is a mutated variant of NRAS Gene (RAS Family), which encodes p21 N-Ras Protein, a monomeric GTPase involved in transmembrane… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
PURPOSE At the molecular level, myeloma is characterized by copy number abnormalities and recurrent translocations into the… (More)
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Highly Cited
2012
Highly Cited
2012
Acquired resistance to EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs) is inevitable in metastatic EGFR-mutant lung cancers… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND There is a need for improved prognostic markers in melanoma. In this study, the authors tested the prognostic… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Oncogenic mutations of PIK3CA, RAS (KRAS, NRAS), and BRAF have been identified in various malignancies, and activate… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Following the discovery that mutant KRAS is associated with resistance to anti-epidermal growth factor receptor (EGFR… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Fifty percent of patients with muscle-invasive bladder cancer (MI-BC) die from their disease and current chemotherapy… (More)
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Highly Cited
2005
Highly Cited
2005
The pathogenesis of acute myeloid leukemia (AML) involves the cooperation of mutations promoting proliferation/survival and those… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Genes of the Raf family encode kinases that are regulated by Ras and mediate cellular responses to growth signals… (More)
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Highly Cited
1999
Highly Cited
1999
Juvenile myelomonocytic leukemia (JMML) is a malignant hematopoietic disorder of early childhood with excessive proliferation of… (More)
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Highly Cited
1988
Highly Cited
1988
In vitro DNA amplification followed by oligonucleotide dot blot analysis were used to study RAS gene mutations in acute myeloid… (More)
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