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N-Methyl-D-Aspartate Receptors

Known as: Receptors, N-Methyl-D-Aspartate, NMDA receptor, Receptors, N-Methylaspartate 
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for… Expand
National Institutes of Health

Related topics

Related topics

26 relations
Calcium ChannelGRIN2A protein, humanGRIN2B protein, humanIn Blood
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Broader (2)

Excitatory Amino Acid ReceptorGlutamate Receptor

Narrower (12)

Gprin1 protein, mouseN-methyl D-aspartate receptor subtype 2ANMDA receptor 2BNMDA receptor A1
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Rapid‐acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective
  • Kenji Hashimoto
  • Psychiatry and clinical neurosciences
  • 2019
    • Corpus ID: 195065228
Major depressive disorder (MDD) is one of the most disabling psychiatric disorders. Approximately one‐third of the patients with… Expand
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Review
2019
Review
2019
Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia
Opioids are a mainstay of acute pain management but can have many adverse effects, contributing to problematic long-term use… Expand
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Highly Cited
2011
Highly Cited
2011
Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
BACKGROUND Despite widely reported clinical and preclinical studies of rapid antidepressant actions of glutamate N-methyl-D… Expand
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Highly Cited
2009
Highly Cited
2009
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents.
OBJECTIVE To report the clinical features of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in patients < or = 18 years… Expand
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Highly Cited
2007
Highly Cited
2007
Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.
OBJECTIVE To report the autoantigens of a new category of treatment-responsive paraneoplastic encephalitis. METHODS Analysis of… Expand
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Highly Cited
2000
Highly Cited
2000
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
Functional activity of N-methyl-D-aspartate (NMDA) receptors requires both glutamate binding and the binding of an endogenous… Expand
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Highly Cited
1998
Highly Cited
1998
Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors.
N-methyl-D-aspartic acid (NMDA) receptors transiently transfected into mammalian HEK-293 cells were characterized with subunit… Expand
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Review
1993
Review
1993
A synaptic model of memory: long-term potentiation in the hippocampus
Long-term potentiation of synaptic transmission in the hippocampus is the primary experimental model for investigating the… Expand
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Highly Cited
1992
Highly Cited
1992
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.
  • S. Dudek, M. Bear
  • Proceedings of the National Academy of Sciences…
  • 1992
    • Corpus ID: 24591658
We tested a theoretical prediction that patterns of excitatory input activity that consistently fail to activate target neurons… Expand
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Highly Cited
1986
Highly Cited
1986
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
Recent work has shown that the hippocampus contains a class of receptors for the excitatory amino acid glutamate that are… Expand
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