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N-Methyl-D-Aspartate Receptors

Known as: Receptors, N-Methyl-D-Aspartate, NMDA receptor, Receptors, N-Methylaspartate 
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for… Expand
National Institutes of Health

Related topics

Related topics

26 relations
Calcium ChannelGRIN2A protein, humanGRIN2B protein, humanIn Blood
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Broader (2)

Excitatory Amino Acid ReceptorGlutamate Receptor

Narrower (12)

Gprin1 protein, mouseN-methyl D-aspartate receptor subtype 2ANMDA receptor 2BNMDA receptor A1
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Paraneoplastic anti–N‐methyl‐D‐aspartate receptor encephalitis associated with ovarian teratoma
To report the autoantigens of a new category of treatment‐responsive paraneoplastic encephalitis. 
Highly Cited
2000
Highly Cited
2000
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
Functional activity of N-methyl-D-aspartate (NMDA) receptors requires both glutamate binding and the binding of an endogenous… Expand
Highly Cited
1998
Highly Cited
1998
Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors.
N-methyl-D-aspartic acid (NMDA) receptors transiently transfected into mammalian HEK-293 cells were characterized with subunit… Expand
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Review
1993
Review
1993
A synaptic model of memory: long-term potentiation in the hippocampus
Long-term potentiation of synaptic transmission in the hippocampus is the primary experimental model for investigating the… Expand
Highly Cited
1993
Highly Cited
1993
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
cDNA clones for four different N-methyl-D-aspartate (NMDA) receptor subunits (NMDAR2A-NMDAR2D) were isolated through polymerase… Expand
Highly Cited
1993
Highly Cited
1993
Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.
  • K. Williams
  • Molecular pharmacology
  • 1993
    • Corpus ID: 31737582
The effects of the atypical N-methyl-D-aspartate (NMDA) receptor antagonist ifenprodil were investigated by voltage-clamp… Expand
Highly Cited
1992
Highly Cited
1992
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.
  • S. Dudek, M. Bear
  • Proceedings of the National Academy of Sciences…
  • 1992
    • Corpus ID: 24591658
We tested a theoretical prediction that patterns of excitatory input activity that consistently fail to activate target neurons… Expand
Highly Cited
1986
Highly Cited
1986
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
Recent work has shown that the hippocampus contains a class of receptors for the excitatory amino acid glutamate that are… Expand
Highly Cited
1985
Highly Cited
1985
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain
N-methyl-D-aspartate (NMDA) is an acidic amino acid which depolarizes neurons by selectively interacting with a distinct class of… Expand
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Highly Cited
1984
Highly Cited
1984
Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain.
In rats ischemia of the forebrain induced by a 30-minute occlusion of the carotid artery, followed by 120 minutes of arterial… Expand
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