Multiple Sclerosis, Chronic Progressive

Known as: Chronic Progressive Multiple Sclerosis, Multiple Sclerosis, Chronic Progressive [Disease/Finding] 
A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
05101519732017

Papers overview

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Highly Cited
2007
Highly Cited
2007
The neurodegenerative aspects of chronic progressive multiple sclerosis (MS) have received increasing attention in recent years… (More)
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Highly Cited
2002
Highly Cited
2002
Blood-brain barrier (BBB) breakdown, demonstrable in vivo by enhanced MRI is characteristic of new and expanding inflammatory… (More)
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Highly Cited
2000
Highly Cited
2000
One of the hallmarks of the human demyelinating disease multiple sclerosis is the inability to compensate adequately for the loss… (More)
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Highly Cited
1999
Highly Cited
1999
In experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin… (More)
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Highly Cited
1996
Highly Cited
1996
A 2-year, placebo-controlled, double-blind, crossover study was started in 1992 to evaluate cladribine, an immunosuppressive drug… (More)
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Highly Cited
1994
Highly Cited
1994
Chronic progressive multiple sclerosis (MS) is a severely disabling demyelinating disease in which autoimmune processes seem to… (More)
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Highly Cited
1993
Highly Cited
1993
Magnetic resonance imaging is a highly sensitive method for the detection of the lesions of multiple sclerosis and renders… (More)
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Highly Cited
1993
Highly Cited
1993
Central nervous system (CNS) remyelination has been found by light and electron microscopy and immunocytochemistry within fresh… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND Cachectin, or tumor necrosis factor-alpha (TNF-alpha), is a principal mediator of the inflammatory response and may be… (More)
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Highly Cited
1984
Highly Cited
1984
Forty-four patients with chronic progressive multiple sclerosis (MS) were compared with age- and education-matched control groups… (More)
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