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Multiple Sclerosis, Chronic Progressive

Known as: Chronic Progressive Multiple Sclerosis, Multiple Sclerosis, Chronic Progressive [Disease/Finding] 
A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing… Expand
National Institutes of Health

Papers overview

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Review
2015
Review
2015
BACKGROUND No drug has been found to have any impact on progressive multiple sclerosis (MS). Biotin is a vitamin acting as a… Expand
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Highly Cited
1999
Highly Cited
1999
In experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin… Expand
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Highly Cited
1996
Highly Cited
1996
A 2-year, placebo-controlled, double-blind, crossover study was started in 1992 to evaluate cladribine, an immunosuppressive drug… Expand
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Highly Cited
1995
Highly Cited
1995
A randomized, double‐blinded, placebo‐controlled, clinical trial of low‐dose, weekly, oral methotrexate was performed in 60… Expand
Highly Cited
1994
Highly Cited
1994
Chronic progressive multiple sclerosis (MS) is a severely disabling demyelinating disease in which autoimmune processes seem to… Expand
Highly Cited
1993
Highly Cited
1993
Magnetic resonance imaging is a highly sensitive method for the detection of the lesions of multiple sclerosis and renders… Expand
Highly Cited
1991
Highly Cited
1991
BACKGROUND Cachectin, or tumor necrosis factor-alpha (TNF-alpha), is a principal mediator of the inflammatory response and may be… Expand
Highly Cited
1990
Highly Cited
1990
Patients with clinically definite multiple sclerosis, mild to moderately severe neurological disability (entry score on the… Expand
Highly Cited
1984
Highly Cited
1984
Forty-four patients with chronic progressive multiple sclerosis (MS) were compared with age- and education-matched control groups… Expand
Review
1983
Review
1983
In an analysis of pooled data, we have found that cytotoxic-suppressor T cells outnumber the helper-inducer subset and also the… Expand