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Multiple Sclerosis, Chronic Progressive

Known as: Chronic Progressive Multiple Sclerosis, Multiple Sclerosis, Chronic Progressive [Disease/Finding] 
A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing… 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The neurodegenerative aspects of chronic progressive multiple sclerosis (MS) have received increasing attention in recent years… 
Highly Cited
2004
Highly Cited
2004
Brain capillaries were analyzed morphometrically for alterations in organelle distribution and density in biopsy samples of… 
Highly Cited
1999
Highly Cited
1999
In experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin… 
Highly Cited
1996
Highly Cited
1996
A 2-year, placebo-controlled, double-blind, crossover study was started in 1992 to evaluate cladribine, an immunosuppressive drug… 
Highly Cited
1995
Highly Cited
1995
A randomized, double‐blinded, placebo‐controlled, clinical trial of low‐dose, weekly, oral methotrexate was performed in 60… 
Highly Cited
1993
Highly Cited
1993
Magnetic resonance imaging is a highly sensitive method for the detection of the lesions of multiple sclerosis and renders… 
Highly Cited
1993
Highly Cited
1993
  • C. RaineE. Wu
  • Journal of Neuropathology and Experimental…
  • 1993
  • Corpus ID: 21868407
Central nervous system (CNS) remyelination has been found by light and electron microscopy and immunocytochemistry within fresh… 
Highly Cited
1991
Highly Cited
1991
BACKGROUND Cachectin, or tumor necrosis factor-alpha (TNF-alpha), is a principal mediator of the inflammatory response and may be… 
Highly Cited
1990
Highly Cited
1990
Patients with clinically definite multiple sclerosis, mild to moderately severe neurological disability (entry score on the… 
Highly Cited
1984
Highly Cited
1984
Forty-four patients with chronic progressive multiple sclerosis (MS) were compared with age- and education-matched control groups…