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Midodrine

Known as: Midodrina, (+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide, DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid 
A direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine… 
National Institutes of Health

Related topics

Related topics

26 relations

Broader (3)

Adrenergic alpha-1 Receptor AgonistsSympathomimeticsVasoconstrictor Agents
Adrenergic alpha1-Agonists [MoA]FludrocortisoneHeart DiseasesHypersensitivity

Narrower (8)

GutronMidonProamatineST 1059

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The alpha‐sympathomimetic midodrin as a tool for diagnosis and treatment of sperm transport disturbances
Summary. The present study was performed to determine the usefulness of the alpha‐sympathomimetic midodrin for diagnosis and… 
2004
2004
Effects of midodrine on exercise-induced hypotension and blood pressure recovery in autonomic failure.
We tested the hypothesis that the oral alpha1-adrenergic agonist, midodrine, would limit the fall in arterial pressure observed… 
2002
2002
Identification and synthesis of some contaminants present in 4-methoxyamphetamine (PMA) prepared by the Leuckart method.
2002
2002
Synthesis of 2-methylpiperazine by photocatalytic reaction in a non-aqueous suspension of semiconductor-zeolite composite catalysts
UV irradiation onto a non-aqueous suspension of semiconductor-zeolite composite catalysts with N -(ß-hydroxypropyl… 
2001
2001
Comparison of alpha 1-adrenoceptor agonists in canine urethral pressure profilometry and abdominal leak point pressure models.
1985
1985
Comparison of the kinetics and mechanism of the papain-catalyzed hydrolysis of esters and thiono esters.
The kinetic constants for the papain-catalyzed hydrolysis of the methyl thiono esters of N-benzoylglycine and N-(beta… 
1982
1982
Covalent cross-linking of a photoactive derivative of calcitonin to human breast cancer cell receptors.
A photoaffinity derivative of salmon calcitonin has been produced by transglutaminase-mediated incorporation of N-(beta… 
Review
1982
Review
1982
Partial ejaculatory incompetence: the therapeutic effect of midodrine, an orally active selective alpha-adrenoceptor agonist.
The syndrome of partial ejaculatory incompetence has been reviewed. 6 patients, diagnosed as suffering from partial ejaculatory… 
1975
1975
Transamidase kinetics. Amide formation in the enzymic reactions of thiol esters with amines.
1. Beta-Phenylpropionylthiocholine and N-(5-aminopentyl)-5-dimethylaminonaphthalene-1-sulphonamide (dansylcadaverine) serve as a… 
1959
1959
Mechanism of drug action at receptor surfaces--II. Chemical reactivity of N-(beta-chloroethyl)-phenoxyethylamines in relation to adrenergic blocking activity.
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