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Microtubule-Associated Proteins 1A/1B Light Chain 3

Known as: Autophagy-Related Protein Lc3, Autophagy-Related Ubiquitin-Like Modifier LC3, MAP1LC3 
A protein family whose members bind to microtubule-associated protein 1A and 1B and are involved in the formation of autophagosomes.
National Institutes of Health

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AutophagyMAP1LC3A geneMAP1LC3A wt AlleleMicrotubule-Associated Proteins 1A/1B Light Chain 3A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for…
2014
2014
Down-Regulation of miRNA-30a Alleviates Cerebral Ischemic Injury Through Enhancing Beclin 1-Mediated Autophagy
The understanding of molecular mechanism underlying ischemia/reperfusion-induced neuronal death and neurological dysfunction may… 
2014
2014
Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function
Circulating angiotensin II (AngII) is elevated in congestive heart failure (CHF), and leads to skeletal muscle wasting, which is… 
2014
2014
Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells
Inhibition of soluble matrix metalloproteinase (MMP) activity is among the non-antibiotic cellular effects exerted by the anti… 
2013
2013
Autophagy is involved in endoplasmic reticulum stress-induced cell death of rat hepatocytes.
2012
2012
SD118-Xanthocillin X (1), a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway
A compound named SD118-xanthocillin X (1) (C18H12N2O2), isolated from Penicillium commune in a deep-sea sediment sample, has been… 
2012
2012
Inhibition of glutamine‐dependent autophagy increases t‐PA production in CHO Cell fed‐batch processes
Understanding the cellular responses caused by metabolic stress is crucial for the design of robust fed‐batch bioprocesses that… 
2012
2012
Emerging role of autophagy during ischemia-hypoxia and reperfusion in hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is the most common primary malignancy found in the liver. Autophagy is the intracellular bulk… 
2011
2011
In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice
2009
2009
Hyperglycemia, intracellular hyaluronan synthesis, cyclin D3 and autophagy
Hyperglycemia is one of the factors that induces autophagy. Our recent studies demonstrate that dividing cells in hyperglycemic… 
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