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MAP1LC3A gene

Known as: ATG8E, LC3A, MICROTUBULE-ASSOCIATED PROTEIN 1, LIGHT CHAIN 3, ALPHA 
This gene plays a role in autophagocytosis.
National Institutes of Health

Related topics

Related topics

5 relations
AutophagyMAP1LC3A protein, humanMicrotubule-Associated Proteins 1A/1B Light Chain 3Microtubule-Associated Proteins 1A/1B Light Chain 3A

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MAP1LC3A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Autophagy in the physiological endometrium and cancer
ABSTRACT Autophagy is a highly conserved catabolic process and a major cellular pathway for the degradation of long-lived… 
Highly Cited
2017
Highly Cited
2017
FKBP8 recruits LC3A to mediate Parkin‐independent mitophagy
Mitophagy, the selective removal of damaged or excess mitochondria by autophagy, is an important process in cellular homeostasis… 
Highly Cited
2015
Highly Cited
2015
Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines
LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether… 
Highly Cited
2014
Highly Cited
2014
TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.
Highly Cited
2014
Highly Cited
2014
Genistein induces apoptosis and autophagy in human breast MCF-7 cells by modulating the expression of proapoptotic factors and oxidative stress enzymes
Breast cancer is one of the common tumors occurring in woman and despite treatment, the prognostic is poor. Genistein, a soy… 
Highly Cited
2013
Highly Cited
2013
Expression of autophagy‐related markers beclin‐1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer
Aims:   To investigate the relationship between the expression of autophagy‐related proteins, including beclin‐1, light chain (LC… 
Highly Cited
2012
Highly Cited
2012
Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive neoplastic disorder arising from T-cell progenitors. T-ALL accounts… 
Highly Cited
2009
Highly Cited
2009
Discovery of Atg5/Atg7-independent alternative macroautophagy
Macroautophagy is a process that leads to the bulk degradation of subcellular constituents by producing autophagosomes… 
Highly Cited
2006
Highly Cited
2006
Molecular cloning and characterization of rat LC3A and LC3B--two novel markers of autophagosome.
Highly Cited
2003
Highly Cited
2003
Post-translational Modifications of Three Members of the Human MAP1LC3 Family and Detection of a Novel Type of Modification for MAP1LC3B*
The molecular machinery required for autophagy is highly conserved in all eukaryotes as seen by the high degree of conservation… 
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