Microtubule-Associated Proteins 1A/1B Light Chain 3

Known as: Autophagy-Related Protein Lc3, Autophagy-Related Ubiquitin-Like Modifier LC3, MAP1LC3 
A protein family whose members bind to microtubule-associated protein 1A and 1B and are involved in the formation of autophagosomes.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C(18)-pyridinium ceramide… (More)
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Review
2011
Review
2011
Autophagy-related (Atg) proteins are eukaryotic factors participating in various stages of the autophagic process. Thus far 34… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Autophagy is a process for turnover of intracellular organelles and molecules that protects cells during stress… (More)
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Highly Cited
2010
Highly Cited
2010
Although 5-fluorouracil (5-FU)-based adjuvant chemotherapy is widely used in the treatment of colorectal cancer, novel… (More)
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Highly Cited
2010
Highly Cited
2010
Elemental metal nanoparticles like cadmium and silver are known to cause oxidative stress and are also highly toxic. Yet for gold… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagy is a highly regulated cellular mechanism for the bulk degradation of cytoplasmic contents which seems to be implicated… (More)
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Highly Cited
2008
Highly Cited
2008
Degenerating neurons of Parkinson's disease (PD) patient brains exhibit granules of phosphorylated extracellular signal-regulated… (More)
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Highly Cited
2008
Highly Cited
2008
Some studies have shown that the change of autophagic capacity may correlate with malignant transformation. Our study was… (More)
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Highly Cited
2006
Highly Cited
2006
A balance between programmed cell death and survival of vascular smooth muscle cells (VSMC) in the fibrous cap, which is… (More)
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Highly Cited
2005
Highly Cited
2005
We tested the hypothesis that chronically ischemic (IS) myocardium induces autophagy, a cellular degradation process responsible… (More)
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