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Metoclopramide Hydrochloride

Known as: Monohydrochloride, Metoclopramide, Metoclopramide Monohydrochloride, Monohydrate, Metoclopramide Monohydrochloride 
The hydrochloride salt of the substituted benzamide metoclopramide, a para-aminobenzoic acid (PABA) derivative that is structurally related to… Expand
National Institutes of Health

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16 relations
Cytochrome P450 2D6, humanEpilepsyGastroesophageal reflux diseaseGastrointestinal Hemorrhage
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MaxolonPrimperanReglan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Formulation and Evaluation of Bi-layer Tablet of Metoclopramide Hydrochloride and Ibuprofen
The aim of this study was to prepare bi-layer tablet of Metoclopramide Hydrochloride (MTH) and Ibuprofen (IB) for the effective… Expand
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2008
2008
Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide.
The work purpose was to study the application of 5-methylpyrrolidinone chitosan (MPC) for preparing mucoadhesive microparticles… Expand
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Highly Cited
2007
Highly Cited
2007
Enhanced bioavailability of metoclopramide HCl by intranasal administration of a mucoadhesive in situ gel with modulated rheological and mucociliary transport properties.
The prolonged residence of drug formulation in the nasal cavity is of utmost importance for intranasal drug delivery. The… Expand
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2006
2006
Nasal absorption of metoclopramide from different Carbopol 981 based formulations: In vitro, ex vivo and in vivo evaluation.
There is a need for nasal drug delivery of metoclopramide HCI (MTC) in specific patient populations where the use of commercially… Expand
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2005
2005
Mucoadhesive microspheres for nasal administration of an antiemetic drug, metoclopramide: in-vitro/ex-vivo studies.
Microparticulate delivery systems designed for the nasal administration of an antiemetic drug, metoclopramide hydrochloride, were… Expand
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2005
2005
Kinetic study of the Maillard reaction between metoclopramide hydrochloride and lactose.
The purpose of this work is to study the apparent solid-state kinetics of the Maillard reaction of the colyophilized… Expand
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1999
1999
Chitosan and chondroitin microspheres for oral-administration controlled release of metoclopramide.
This study investigated the usefulness of chitosan and chondroitin sulphate microspheres for controlled release of metoclopramide… Expand
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Highly Cited
1993
Highly Cited
1993
The prevalence of metoclopramide-induced tardive dyskinesia and acute extrapyramidal movement disorders.
BACKGROUND Metoclopramide hydrochloride, a neuroleptic dopamine receptor antagonist used to treat gastric ailments, is reported… Expand
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1982
1982
Intravenous metoclopramide. An effective antiemetic in cancer chemotherapy.
An open-label clinical trial was conducted to test the safety and efficacy of intravenous metoclopramide monohydrochloride in… Expand
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1977
1977
Substituted benzamides as cerebral dopamine antagonists in rodents
Abstract The substituted benzamides metoclopramide, sulpiride, tigan and clebopride and its debenzylated metabolite (DP) were… Expand
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