Metastatic melanoma

Known as: melanoma, metastatic, melanoma stage iv, stage iv melanoma 
A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The first evidence that radiotherapy enhances the efficacy of immune checkpoint blockers (ICB) was obtained a dozen years ago in… (More)
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Review
2017
Review
2017
Oncolytic viruses (OVs) are opening new possibilities in cancer therapy with their unique mechanism of selective replication… (More)
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Review
2017
Review
2017
The incidence of malignant melanoma has continued to rise during the past decades. However, in the last few years, treatment… (More)
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Review
2017
Review
2017
BACKGROUND Immune checkpoint inhibitors and targeted therapies, two new class of drugs for treatment of metastatic melanoma, have… (More)
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Review
2017
Review
2017
BACKGROUND Anti-PD-1 monoclonal antibodies, nivolumab and pembrolizumab, and anti-CTLA-4 antibody ipilimumab are being in clinic… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Nivolumab was associated with higher rates of objective response than chemotherapy in a phase 3 study involving… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Dabrafenib, an inhibitor of mutated BRAF, has clinical activity with a manageable safety profile in studies of phase 1… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The identification of somatic mutations in the gene encoding the serine-threonine protein kinase B-RAF (BRAF) in the… (More)
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