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Metastatic melanoma

Known as: melanoma, metastatic, melanoma stage iv, stage iv melanoma 
A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
National Institutes of Health

Related topics

Related topics

8 relations
Body tissueMIR222 geneMIR222 wt AlleleMelanoma Cell

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Stage IV Skin Melanoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
Highly Cited
2015
Highly Cited
2015
Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma
Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral… 
Highly Cited
2014
Highly Cited
2014
Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trial.
IMPORTANCE Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) blockade with ipilimumab prolongs survival in patients with… 
Highly Cited
2013
Highly Cited
2013
Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
Purpose: Adoptive cell transfer (ACT) using autologous tumor-infiltrating lymphocytes (TIL) was reported to yield objective… 
Highly Cited
2008
Highly Cited
2008
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
Blockade of inhibitory signals mediated by cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) has been shown to enhance T cell… 
Highly Cited
2008
Highly Cited
2008
Treatment of Metastatic Melanoma Using Interleukin-2 Alone or in Conjunction with Vaccines
Purpose: To identify prognostic factors associated with survival beyond 4 years and overall response in patients with metastatic… 
Highly Cited
2005
Highly Cited
2005
Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies.
PURPOSE Individuals with metastatic melanoma have a poor prognosis. Many human melanomas are auxotrophic for arginine, and… 
Highly Cited
2001
Highly Cited
2001
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
CDKN2A (INK4a/ARF) is frequently disrupted in various types of human cancer, and germline mutations of this locus can confer… 
Review
1996
Review
1996
Surgical resection for melanoma metastatic to the gastrointestinal tract.
OBJECTIVE To evaluate the role of surgery in the survival of patients with melanoma metastatic to the gastrointestinal (GI) tract… 
Highly Cited
1995
Highly Cited
1995
Sentinel lymph node status as an indicator of the presence of metastatic melanoma in regional lymph nodes
The value of elective lymph node dissection (ELND) for melanoma patients with clinically uninvolved regional nodes remains… 
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