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Metachromatic Leukodystrophy, Adult-Type (disorder)

Known as: Leukodystrophies, Adult-Type Metachromatic, Adult Metachromatic Leukodystrophy, Leukodystrophy, Adult-Type Metachromatic 
National Institutes of Health

Related topics

Related topics

3 relations
Arylsulfatase A Deficiency

Broader (2)

LeukodystrophyLeukodystrophy, Metachromatic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor
Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder of the brain caused by mutations in the gene encoding the… 
2013
2013
Improvement of white matter changes on neuroimaging modalities after stem cell transplant in metachromatic leukodystrophy.
IMPORTANCE We sought to illustrate improvement of cerebral white matter changes in metachromatic leukodystrophy after treatment… 
Highly Cited
2002
Highly Cited
2002
Bone marrow stem cell-based gene transfer in a mouse model for metachromatic leukodystrophy: effects on visceral and nervous system disease manifestations
Arylsulfatase A (ASA) knockout mice represent an animal model for the lysosomal storage disease metachromatic leukodystrophy (MLD… 
Highly Cited
1977
Highly Cited
1977
Myelination of mouse axons by Schwann cells transplanted from normal and abnormal human nerves
IN mouse nerve iso- and allografts, Schwann cells transplanted from the donor animal survive, multiply within the graft and… 
Highly Cited
1971
Highly Cited
1971
A correlation of intracellular cerebroside sulfatase activity in fibroblasts with latency in metachromatic leukodystrophy.
Highly Cited
1971
Highly Cited
1971
Correction of Abnormal Cerebroside Sulfate Metabolism in Cultured Metachromatic Leukodystrophy Fibroblasts
Cultured fibroblasts derived from patients with late infantile metachromatic leukodystrophy incorporated arylsulfatase A from the… 
Highly Cited
1970
Highly Cited
1970
Infantile metachromatic leukodystrophy.
Abstract A profound deficiency of arylsulfatase A activity (ARA) is detectable in skin fibroblasts developed from patients with… 
Review
1968
Review
1968
Metachromatic Leukodystrophy (MLD): VIII. MLD in Adults; Diagnosis and Pathogenesis
ADULTS, as well as children, develop metachromatic leukodystrophy (MLD). Does the adult with MLD also have a sulfatase A… 
Highly Cited
1965
Highly Cited
1965
EVIDENCE FOR THE GENETIC BLOCK IN METACHROMATIC LEUCODYSTROPHY (ML).
1962
1962
Peripheral Nerve Changes in the Diagnosis of Metachromatic Leucodystrophy
A histopathological study was made on peripheral nerves and spinal roots from biopsies and autopsies of 8 cases with… 
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