Leukodystrophy, Metachromatic

Known as: leukodystrophy metachromatic, Arylsulfatase A Deficiency Disease, Metachromatic Leukoencephalopathies 
An autosomal recessive inherited disorder characterized by abnormalities in the development of the myelin sheaths. It is caused by a deficiency of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Metachromatic leukodystrophy (MLD) is an inherited lysosomal storage disease caused by arylsulfatase A (ARSA) deficiency… (More)
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Highly Cited
2011
Highly Cited
2011
Many children have significant mathematical learning disabilities (MLD, or dyscalculia) despite adequate schooling. The current… (More)
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Highly Cited
2007
Highly Cited
2007
Using strict and lenient mathematics achievement cutoff scores to define a learning disability, respective groups of children who… (More)
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Highly Cited
2006
Highly Cited
2006
Metachromatic leukodystrophy (MLD) is a demyelinating lysosomal storage disorder for which new treatments are urgently needed. We… (More)
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Highly Cited
2004
Highly Cited
2004
Gene-based delivery can establish a sustained supply of therapeutic proteins within the nervous system. For diseases… (More)
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Review
2003
Review
2003
The classic globoid cell leukodystrophy (Krabbe's disease) is caused by genetic defects in a lysosomal enzyme… (More)
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Highly Cited
2002
Highly Cited
2002
Patients with Hurler syndrome (mucopolysaccharidosis type-IH) and metachromatic leukodystrophy (MLD) develop significant skeletal… (More)
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Highly Cited
2001
Highly Cited
2001
Metachromatic leukodystrophy (MLD) is a lipidosis caused by deficiency of arylsulfatase A (ARSA). Although the genetics of MLD… (More)
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Review
1999
Review
1999
Over 400 patients with lysosomal and peroxisomal storage diseases have received hematopoietic stem cell transplantation from… (More)
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Highly Cited
1996
Highly Cited
1996
Metachromatic leukodystrophy is a lysosomal sphingolipid storage disorder caused by the deficiency of arylsulfatase A. The… (More)
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