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Metabotropic Glutamate Receptor 1, human

Known as: MGLUR1-Alpha, GRM1-Alpha, Metabotropic Glutamate Receptor 1 
Metabotropic glutamate receptor 1 (1194 aa, ~132 kDa) is encoded by the human GRM1 gene. This protein plays a role in in G protein-coupled receptor… 
National Institutes of Health

Related topics

Related topics

14 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingGRM1 geneGRM1 wt Allele

Broader (1)

metabotropic glutamate receptor type 1

Papers overview

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2017
2017
New Approaches to Melanoma Treatment: Checkpoint Inhibition with Novel Targeted Therapy
Melanoma is the most dangerous type of skin cancer, largely due to its propensity for recurrence and metastasis, even after… 
2013
2013
Abstract 5082: Pre-clinical study targeting metabotropic glutamate receptor (GRM1) angiogenesis pathway.
2012
2012
Abstract 81: Role of GRM1 in breast cancer
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Despite epidemiologic studies suggesting a link… 
2010
2010
A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in metastatic melanoma.
8557 Background: Preclinical studies demonstrate that GRM1 is a potential therapeutic target in melanoma, with > 60% of human… 
Review
2010
Review
2010
Role of the G Protein-Coupled Receptor, mGlu1, in Melanoma Development
Melanoma remains one of the cancers for which a decline in morbidity has not been achieved with current scientific and medical… 
2009
2009
Effects of riluzole (RZ) and ionizing radiation (IR) in metabotropic glutamate receptor-1 (GRM1) positive human melanoma.
9083 Background: Melanoma has long been known to be relatively radio-resistant. GRM1 is a metabotropic glutamate receptor that… 
2009
2009
K + CHANNELS AND THE REGULATION OF SYNAPTIC TRANSMISSION
Neuronal excitability is highly regulated by K channels that are activated by a voltage change across the plasma membrane or by a… 
2007
2007
Transcriptional Activators and Repressors for the Neuron-specific Expression of a Metabotropic
2005
2005
The mRNA changes of metabotropic glutamate receptor 1 (mGluRl) and metabotropic glutamate receptor 5 (mGluR5) in rats with focal cerebral ischemia and reperfusion
Objective: To investigate the mRNA changes of metabotropic glutamate receptor 1 (mGluRI ) and metabo tropic glutamate receptor 5… 
2004
2004
Agonist-dependent and -independent internalization of metabotropic glutamate receptor 1.