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Metabotropic Glutamate Receptor 1, human

Known as: MGLUR1-Alpha, GRM1-Alpha, Metabotropic Glutamate Receptor 1 
Metabotropic glutamate receptor 1 (1194 aa, ~132 kDa) is encoded by the human GRM1 gene. This protein plays a role in in G protein-coupled receptor… 
National Institutes of Health

Related topics

Related topics

14 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingGRM1 geneGRM1 wt Allele

Broader (1)

metabotropic glutamate receptor type 1

Papers overview

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2016
2016
Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach
Metabotropic glutamate receptor 1 (mGluR1) is considered as an attractive drug target for neuropathic pain treatments. The… 
2013
2013
Cerebellar degeneration associated with mGluR1 autoantibodies as a paraneoplastic manifestation of prostate adenocarcinoma
Highly Cited
2012
Highly Cited
2012
Metabotropic Glutamate Receptor 1 (Grm1) Is An Oncogene In Epithelial Cells
Non-neuronal expression of components of the glutamatergic system has been increasingly observed, and our laboratory previously… 
Highly Cited
2011
Highly Cited
2011
Clustered Coding Variants in the Glutamate Receptor Complexes of Individuals with Schizophrenia and Bipolar Disorder
Current models of schizophrenia and bipolar disorder implicate multiple genes, however their biological relationships remain… 
2003
2003
Immunolocalization of the acid-sensing ion channel 2a in the rat cerebellum
The acid-sensing ion channels (ASICs) are members of the DEG/ENaC superfamily of Na+ channels. Acid-gated cation currents have… 
Highly Cited
2001
Highly Cited
2001
Characterization of the mGluR(1)-mediated electrical and calcium signaling in Purkinje cells of mouse cerebellar slices.
The metabotropic glutamate receptor 1 (mGluR(1)) plays a fundamental role in postnatal development and plasticity of ionotropic… 
2001
2001
Augmented motor activity and reduced striatal preprodynorphin mRNA induction in response to acute amphetamine administration in metabotropic glutamate receptor 1 knockout mice
1999
1999
Cloning of novel splice variants of mouse mGluR1.
Highly Cited
1998
Highly Cited
1998
Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat
1996
1996
Chronic ethanol on mRNA levels of IP3R1, IP3 3‐kinase and mGluR1 in mouse Purkinje neurons
Chronic ethanol exposure is known to alter the poly-phosphoinositide (poly-PI) signaling pathway, although the exact sight of… 
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